PMID: 6168354Mar 15, 1981Paper

Tumor markers of pancreatic carcinoma

Cancer
J V Klavins

Abstract

There is no well-defined specific tumor marker for carcinoma of the pancreas. Carcinoembryonic antigen (CEA) and alphafetal protein (AFP) are produced by some pancreatic cancer cells. A pancreatic oncofetal antigen (POA) cross-reacts with other malignant neoplasms and is not produced by all pancreatic carcinomas. An ammonium sulfate fraction (0-25%) from an aqueous extract of pancreatic carcinoma tissues contains an antigen cross-reacting with extracts of other pancreatic carcinomas and various carcinomas representing all three germinal layers. A heterologous antiserum to this antigen cross-reacts with sera from patients with pancreatic carcinomas in a dilution of 1:16,000. At lower dilutions this antiserum reacts with sera from patients with other carcinomas and with sera from some apparently healthy individuals.

References

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Citations

Jul 1, 2008·The Journal of Obstetrics and Gynaecology Research·Takafumi WatanabeAkira Sato
Oct 1, 1987·Acta Pathologica Japonica·Y OhakiM Hirose
Dec 1, 1984·World Journal of Surgery·I Ihse, G Isaksson
Dec 1, 1990·Baillière's Clinical Gastroenterology·J M Rhodes, C K Ching

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