PMID: 15253047Jul 16, 2004Paper

Tumor prevalence and biomarkers of exposure in brown bullhead (Ameiurus nebulosus) from Back River, Furnace Creek, and Tuckahoe River, Maryland

Archives of Environmental Contamination and Toxicology
Alfred E PinkneyM J Melancon

Abstract

Brown bullheads (Ameiurus nebulosus) were collected from 2 locations near Baltimore, Maryland, Back River and Furnace Creek, and 1 (reference) location, Tuckahoe River, to compare the prevalence of tumors (liver and skin) and visible skin lesions (fin erosion and abnormal barbels). Cytochrome P450 activity measured as ethoxyresorufin-O-deethylase, biliary PAH-like fluorescent metabolites, and fillet contaminant concentrations were determined as indicators of exposure in a randomly selected subset of the fish. There were no significant differences in liver tumor prevalence: Back River = 8% (4/50), Furnace Creek = 0% (0/50), and Tuckahoe River = 2.6% (1/39; p = 0.20, extension of Fisher's exact test). Skin tumor prevalence was as follows: Furnace Creek = 12% (6/50), Back River = 8% (4/50), and Tuckahoe River = 0% (0/39; p = 0.063). In the Back River fish, there was a 40% (20/50) prevalence of fin erosion and a 28% (14/50) prevalence of abnormal (shortened, clubbed, or missing) barbels. Fin erosion was not observed in the other collections, and only 10% (5/50) of the Furnace Creek fish had abnormal barbels (p < 0.001 for both lesions). There were statistically significant differences in mean EROD activity, with levels in Furnace C...Continue Reading

Citations

Oct 3, 2012·Environmental Toxicology and Chemistry·Eve A M GilroyJames P Sherry
Sep 15, 2011·Journal of Environmental Monitoring : JEM·F GagnéM Hewitt
Apr 17, 2020·Scientific Reports·Erin L PulsterSteven A Murawski
Oct 31, 2009·Journal of Aquatic Animal Health·Alfred E PikneyMichael A Rutter
Feb 24, 2010·Journal of Environmental Quality·Carole Di GiorgioMichel De Méo
Dec 1, 2006·Journal of Aquatic Animal Health·Alfred E Pinkney, John C Harshbarger

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