PMID: 326683Jun 15, 1977Paper

Tumor regression after intralesional injection of emulsified trehalose-6,6'-dimycolate (cord factor): efficacy increases with oil concentration

International Journal of Cancer. Journal International Du Cancer
E YarkoniH J Rapp

Abstract

Injection of emulsified trehalose-6,6'-dimycolate (TDM), a mycobacterial glycolipid, into transplants of an established, syngeneic murine fibrosarcoma induced complete regression of tumor in a number of animals. The number of animals in wich tumor regressed completely depended on the amount of oil in the emulsion. The anti-tumor activity of the TDM emulsion containing the highest concentration of oil was equivalent to that of living BCG.

References

Nov 1, 1975·Journal of the National Cancer Institute·E E RibiS M Strain
Apr 1, 1977·Infection and Immunity·E YarkoniA Bekierkunst
Mar 1, 1976·Infection and Immunity·R SaitoY Yamamura
Mar 1, 1976·Chemistry and Physics of Lipids·E Lederer
Oct 1, 1968·Journal of Bacteriology·A Bekierkunst
Oct 1, 1969·Journal of Bacteriology·A BekierkunstE Lederer

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Citations

Mar 1, 1981·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E YarkoniJ T Hunter
Dec 1, 1980·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M V PimmE Lederer
Nov 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E YarkoniM S Meltzer
Jul 1, 1986·Medicinal Research Reviews·G LemaireE Lederer
Nov 15, 1978·International Journal of Cancer. Journal International Du Cancer·E YarkoniE Lederer
Dec 15, 1979·International Journal of Cancer. Journal International Du Cancer·M V PimmE Lederer

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