Tumor suppressors: a developing role for p53?

Current Biology : CB
P A Hall, D P Lane

Abstract

An increasing body of evidence indicates that p53, the product of a tumour suppressor gene, has a role in development - could this developmental role have provided the primary driving force in the evolution of a protein best known as a stress-response integrator?

References

Aug 1, 1995·Current Biology : CB·J F ArmstrongA R Clarke
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·T NakamuraH Westphal
Jun 1, 1995·Nature Genetics·V P SahT Jacks
May 1, 1996·Nature Medicine·T NorimuraS Kondo
May 1, 1996·Genes & Development·L J Ko, C Prives
Aug 2, 1996·Journal of Molecular Biology·T Soussi, P May
Jan 1, 1996·Current Biology : CB·J A WubahT B Knudsen
Sep 1, 1996·The Journal of Pathology·P A HallD P Lane

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Citations

Dec 2, 1999·The Journal of General Virology·A Marti, K Ballmer-Hofer
Jan 26, 2005·British Journal of Cancer·A J MunroD P Lane
Mar 24, 2007·Nature Reviews. Molecular Cell Biology·Karen H Vousden, David P Lane
Sep 6, 2008·Birth Defects Research. Part C, Embryo Today : Reviews·Nadia DanilovaShuo Lin
Jan 8, 2009·International Journal of Dermatology·Marko LensK P Wilhelm
Jan 23, 2013·International Journal of Molecular Medicine·Yevgeny TendlerGary Weisinger
Nov 1, 2013·Cell & Bioscience·Min Hwa ShinJing Huang
Nov 21, 1998·The British Journal of Surgery·R J SteeleD P Lane
Apr 9, 1999·Biological Chemistry·M HerzigG Christofori
Oct 21, 1999·Journal of Cellular Physiology·Y ChenH K Chew
Dec 18, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·P Lichtlen, W Schaffner
Jul 9, 2002·Molecular and Cellular Biology·Domenico MiglioriniJean-Christophe Marine
Feb 4, 2003·Nature Reviews. Cancer·Andrei V Gudkov, Elena A Komarova
May 16, 2009·Biochemical Society Transactions·Karen H Vousden
Aug 29, 2006·World Journal of Gastroenterology : WJG·Nicola FiedlerStephan Schaefer
Nov 2, 2007·The Journal of Pathology·P J Coates
Jun 22, 2019·Journal of Molecular Cell Biology·David P Lane, Chandra S Verma
Apr 30, 2003·Cell Death and Differentiation·A R Clarke, M Hollstein
May 26, 1999·The Journal of Pathology·C Prives, P A Hall
Apr 16, 1998·Springer Seminars in Immunopathology·R V Sionov, Y Haupt
Mar 13, 2013·Apoptosis : an International Journal on Programmed Cell Death·Debora Lo FurnoVenera Cardile
Dec 16, 1998·Developmental Biology·Y YinA Morgentaler
Feb 24, 2001·Theriogenology·D H Betts, W A King
Apr 5, 2001·Toxicology in Vitro : an International Journal Published in Association with BIBRA·L MarrotC Agapakis-Causse
May 2, 2002·Biochimica Et Biophysica Acta·Jerson L SilvaDébora Foguel
Jan 22, 1998·Mutation Research·P G WellsL M Winn
Jul 4, 1998·Mechanisms of Development·T LéveillardB Wasylyk
Jun 4, 1999·Trends in Genetics : TIG·S Y Foo, G P Nolan
Apr 10, 1999·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·I Salles-PassadorR Fotedar
Jun 5, 2003·Mechanisms of Ageing and Development·Armando Aranda-Anzaldo, Myrna A R Dent

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