Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Alberto MantovaniAntonio Sica

Abstract

Macrophages are versatile, plastic cells which respond to micro-environmental signals with distinct functional programmes. In the tumour microenvironment, tumour-associated macrophages (TAM) polarise towards a type II phenotype, oriented to the promotion of tissue remodelling and repair. As polarised type II macrophages, TAM are a key component of the inflammatory circuits that promote tumour progression.

References

Nov 1, 1992·Immunology Today·G Opdenakker, J Van Damme
Jul 1, 1992·Immunology Today·A MantovaniL Ruco
Nov 12, 1998·Journal of the National Cancer Institute·L M Wahl, H K Kleinman
Nov 12, 1998·Journal of the National Cancer Institute·I B Joseph, J T Isaacs
Dec 5, 1998·International Journal of Immunopharmacology·D W MullinsK D Elgert
Jun 4, 1999·Immunology Today·A Mantovani
Mar 7, 2001·Lancet·F Balkwill, A Mantovani
Mar 21, 2001·The Journal of Experimental Medicine·E Y LinJ W Pollard
May 30, 2001·Trends in Immunology·A MantovaniP Allavena
Dec 6, 2001·The Journal of Experimental Medicine·S IbeT Blankenstein
Jan 5, 2002·Journal of Immunotherapy·V BronteP Zanovello
Jun 26, 2002·Journal of Immunological Methods·UNKNOWN IUIS/WHO Subcommittee on Chemokine Nomenclature
Sep 6, 2002·The American Journal of Pathology·Sebastian F SchoppmannDontscho Kerjaschki
Dec 20, 2002·Nature·Lisa M Coussens, Zena Werb
Jan 4, 2003·Nature Reviews. Immunology·Siamon Gordon
Jan 30, 2003·Journal of Leukocyte Biology·David M Mosser
Mar 12, 2003·Cell·Thorsten CramerRandall S Johnson
Apr 17, 2003·Journal of the National Cancer Institute·Jean-Philippe HerbeuvalChristian Genin
Jun 18, 2003·Trends in Immunology·Vincenzo BrontePaola Zanovello
Nov 5, 2003·The Journal of Experimental Medicine·Tiziana SchioppaAntonio Sica
Jan 7, 2004·Nature Reviews. Cancer·Jeffrey W Pollard
Dec 21, 2004·International Journal of Cancer. Journal International Du Cancer·Yumiko OhnoMasaki Inoue
Mar 14, 2007·International Journal of Cancer. Journal International Du Cancer·Peter W SzlosarekFrances R Balkwill
Oct 24, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A P G CrijnsE G E de Vries

❮ Previous
Next ❯

Citations

Dec 8, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Kenneth Wilfried KrossHans Jørgen Aarstad
Oct 10, 2006·Cancer Metastasis Reviews·Michael R ShurinRobert L Ferris
Dec 11, 2007·Cancer Metastasis Reviews·David G DeNardoLisa M Coussens
Nov 13, 2008·Clinical & Experimental Metastasis·Yi LuJian Zhang
Aug 24, 2010·Journal of Mammary Gland Biology and Neoplasia·Johanna R Reed, Kathryn L Schwertfeger
Dec 17, 2010·Journal of Mammary Gland Biology and Neoplasia·Stephen L Shiao, Lisa M Coussens
Mar 7, 2012·Immunologic Research·Marija MilovanovicMiodrag L Lukic
Mar 7, 2013·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·P J VlachostergiosC N Papandreou
Sep 29, 2011·Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society·Antonio SicaElena Riboldi
Jun 1, 2005·Cancer Letters·Monica MolteniCarlo Rossetti
Jan 12, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Sylvia HartmannMartin-Leo Hansmann
Feb 18, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shuei-Liong LinJeremy S Duffield
Jul 27, 2007·Molecular Biology of the Cell·Andreas WeigertBernhard Brüne
Sep 19, 2008·Journal of Pediatric Hematology/oncology·Paul T JubinskyMary K Short
Nov 26, 2013·The Cancer Journal·Sabine Hensler, Margareta M Mueller
Mar 17, 2010·Antimicrobial Agents and Chemotherapy·David J FeolaBrian S Murphy
Jun 24, 2008·Molecular Cancer Research : MCR·Krishna ReddyEugenie S Kleinerman
Jul 25, 2006·The Journal of Clinical Investigation·Yunping LuoRong Xiang
Mar 3, 2007·The Journal of Clinical Investigation·Alessia Meneghin, Cory M Hogaboam
Aug 13, 2008·Blood·Alessandra MancinoAntonio Sica
Mar 24, 2005·Journal of Leukocyte Biology·Evemie SchutyserJo Van Damme
Jun 23, 2012·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Sherrill L MacuraBrooke T Mossman
Apr 2, 2009·Biological Chemistry·Andreas WeigertBernhard Brüne
Jan 1, 2009·Immunotherapy·Andreas WeigertBernhard Brüne
May 31, 2011·Frontiers in Bioscience (Scholar Edition)·Rajesh SinghShailesh Singh
Dec 10, 2013·Vascular Cell·Chunqing GuoXiang-Yang Wang
Aug 3, 2012·Immunotherapy·Claudia Cocco, Irma Airoldi
Aug 8, 2006·Proceedings of the National Academy of Sciences of the United States of America·Hiroaki NozawaDouglas Hanahan
Apr 10, 2014·Apoptosis : an International Journal on Programmed Cell Death·Bettina M KaminskiSandra Ulrich-Rückert
Mar 7, 2012·Cancer Immunology, Immunotherapy : CII·Alexander L RakhmilevichPaul M Sondel
Jan 29, 2011·Seminars in Immunopathology·Takeshi NakajimaPatricia W Finn
Oct 4, 2011·Translational Oncology·Irina Kareva
Jul 19, 2012·International Reviews of Immunology·Alexander L RakhmilevichPaul M Sondel

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