Jul 1, 1983

Tumour marker acquisition in the polyp-to-cancer sequence in the colon

European Journal of Cancer & Clinical Oncology
R Whitehead, J M Skinner

Abstract

Sequential studies of 6 tumour markers in an adenomatous polyp which eventually metastesized as adenocarcinoma are described. The findings suggest that with the development of malignancy, clones of cells with an increasing number of markers are favoured for continued growth and that this probably represents progressive gene derepression.

  • References3
  • Citations3

Citations

Mentioned in this Paper

Human Placental Lactogen
Polyps
Neoplasms
Tumor Lysis Syndrome
Malignant Tumor of Colon
Carcinoembryonic Antigen
Alkaline Phosphatase
Primary Malignant Neoplasm
Adenocarcinoma
Carcinoma, Cribriform

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