Tumour volume of resectable oesophageal squamous cell carcinoma measured with MRI correlates well with T category and lymphatic metastasis

European Radiology
Lan WuJin-Ming Cao

Abstract

To determine association of gross tumour volume (GTV) of resectable oesophageal squamous cell carcinoma (SCC) measured on T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE-T1WI) and diffusion-weighted imaging (DWI) with T category and lymphatic metastasis (LM). Sixty oesophageal SCC patients underwent fat-suppressed T2WI, CE-T1WI and DWI with b values of 0, 500 and 800 s/mm2. GTV was measured on three sequences. Statistical analyses were performed to determine association of GTV with T category and LM. Spearman's rank correlation analysis showed positive association of GTV with T category and LM (all p values < 0.01). Differences in GTV were found between T1 and T2 or T3 categories shown by Kruskal-Wallis H and one-way ANOVA tests, and between T1/T2 and T3 and between tumours with and without LM by Mann-Whitney U tests (all p values < 0.05). Receiver operating characteristic analyses showed cut-off GTVs of 5.795, 5.276 and 10.11 cm3 on CE-T1WI could better differentiate T1 from T2 categories, T1 from T3, and T1-2 from T3 than those of 7.066, 7.045 and 8.504 cm3 on T2WI, of 5.793, 6.609 and 6.989 cm3 on DWI with b value of 500 s/mm2, and of 4.156, 4.519 and 4.985 cm3 with b value of 800 s/mm2, respectively. C...Continue Reading

References

Jan 1, 1994·Surgical and Radiologic Anatomy : SRA·G MurakamiT Imazeki
Apr 1, 1996·The British Journal of Radiology·E Y LiangC Metreweli
Dec 7, 2006·American Journal of Clinical Oncology·Gilles CréhangeJean François Bosset
Oct 24, 2007·AJR. American Journal of Roentgenology·Nagihan InanAli Demirci
Dec 19, 2007·Journal of Gastroenterology and Hepatology·Dong Uk KimYoung Mog Shim
Mar 26, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Karim SillahIan M Welch
Mar 1, 2011·The Annals of Thoracic Surgery·Bing-Yen WangYu-Chung Wu
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Feb 19, 2015·Journal of the National Comprehensive Cancer Network : JNCCN·Jaffer A AjaniUNKNOWN National comprehensive cancer network
Jun 23, 2016·Journal of Chiropractic Medicine·Terry K Koo, Mae Y Li
Jan 31, 2017·The British Journal of Radiology·Francesco GigantiFrancesco De Cobelli
Mar 21, 2017·Journal of Surgical Oncology·Gautam K MalhotraChandrakanth Are
May 16, 2017·Hematology/oncology Clinics of North America·Thomas HayesWilliam Allum

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.