Tuning the dynamics and molecular distribution of the self-spreading lipid bilayer

Physical Chemistry Chemical Physics : PCCP
Hideki NabikaKei Murakoshi

Abstract

The self-spreading dynamics of lipid bilayers were investigated at controlled electrolyte concentrations. The self-spreading velocity increased when the concentration of NaCl was increased from 1 to 100 mM. Comparing the experimentally determined spreading energy with that estimated from theoretical models, we found that the self-spreading dynamics were well explained by considering the van der Waals interaction, double layer interaction and hydration interaction energies between the self-spreading bilayer and the substrate. The characteristic behavior at high concentration is attributable to the increase in the density of the lipid layer, originating from the effective shielding of the molecular charges by the electrolyte ions in solution. The distribution of doped dye-labeled molecule within the spreading bilayer was also controllable by tuning the electrolyte concentration. All of these findings were explained by systematic changes in bilayer-substrate or inter-molecular interactions depending on the electrolyte concentration.

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Jan 11, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Kazuaki FurukawaKeiichi Torimitsu

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Citations

Dec 18, 2013·Molecular Membrane Biology·Lorena Redondo-MorataFausto Sanz
Oct 16, 2015·Chemical Communications : Chem Comm·Joshua A JackmanNam-Joon Cho
Oct 20, 2010·Nanoscale·Baku TakimotoKei Murakoshi
Aug 23, 2019·Journal of Biological Physics·Vladimir P Zhdanov
Dec 20, 2008·Analytical Chemistry·Hideki NabikaKei Murakoshi
Aug 2, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Joshua A JackmanNam-Joon Cho
Dec 17, 2014·ACS Applied Materials & Interfaces·Joshua A JackmanNam-Joon Cho
Feb 12, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Joshua A JackmanNam-Joon Cho
May 7, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Joshua A JackmanNam-Joon Cho
Oct 27, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·J Tucker AndrewsPeter J N Kett

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