Turbidimetric kinetic method for serum low density lipoprotein quantitation

Clinica Chimica Acta; International Journal of Clinical Chemistry
K BartlG Assmann

Abstract

A turbidimetric kinetic fixed-time method for the rapid determination of serum low density lipoprotein (LDL) has been developed. It is based on specifically precipitating this lipoprotein with the use of a combination of heparin, Ca2+, EDTA and lipase. The method has been adapted to the Eppendorf spectrum line photometer and to the ENI Gemsaec centrifugal analyzer. It yielded satisfactory results with regard to linearity and precision. The values agreed closely to those obtained by conventional procedures for LDL-cholesterol and LDL-apolipoprotein B. The predictive value of this new method for the assessment of the individual risk of vascular disease remains to be proven by clinical and epidemiological studies.

References

Nov 1, 1970·Atherosclerosis·S R SrinivasanG S Berenson
May 8, 1981·Science·M S BrownJ L Goldstein

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Citations

Mar 27, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·G Assmann, H U Jabs
Feb 13, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·G BurnsD Seidel
Apr 1, 1985·Clinical Biochemistry·L KerscherJ Ziegenhorn

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