DOI: 10.1101/459271Nov 1, 2018Paper

Turning and twisting motion of chromosomes as an accelerating force to align homologous chromosomes during meiosis

BioRxiv : the Preprint Server for Biology
Kazutaka TakaoAkinori Awazu

Abstract

Homologous sets of parental chromosomes must pair during meiosis to produce recombined sets of chromosomes for their progeny. This is accompanied by nuclear oscillatory movements. This study aimed to elucidate the significance of these movements with a model, wherein external force was applied to the oscillating nucleus and via hydrodynamic interactions within the nucleus. Simulations revealed that a major force for aligning homologous chromosomes is length-dependent sorting during chromosomal turning and twisting, which occur when the nucleus reverses the direction of its movement.

Related Concepts

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

Health Management Quarterly : HMQ
J Horty
Cold Spring Harbor Symposia on Quantitative Biology
L R Bell, B Byers
Rivista italiana di ginecologia
M GirottiG A Hauser
© 2021 Meta ULC. All rights reserved