Turning Photons into Drugs: Phthalocyanine-Based Photosensitizers as Efficient Photoantimicrobials.

Chemistry : a European Journal
Anzhela Galstyan

Abstract

One of the most promising alternatives for treating bacterial infections is antimicrobial photodynamic therapy (aPDT), making the synthesis and application of new photoactive compounds called photosensitizers (PS) a dynamic research field. In this regard, phthalocyanine (Pc) derivatives offer great opportunities due to their extraordinary light-harvesting and tunable electronic properties, structural versatility, and stability. This Review, rather than focusing on synthetic strategies, intends to overview current progress in the structural design strategies for Pcs that could achieve effective photoinactivation of microorganisms. In addition, the Review provides a concise look into the recent developments and applications of nanocarrier-based Pc delivery systems.

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Citations

Jan 15, 2021·Chemistry : a European Journal·Miguel Ángel Revuelta-MazaGema de la Torre
May 25, 2021·Bioconjugate Chemistry·Asma RahaliEduardo Anaya-Plaza
Oct 6, 2021·Materials Horizons·Jiayu ZengXuemei Wang
Oct 28, 2021·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Rafael T ArosoMariette M Pereira
Nov 17, 2021·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Nidia Maldonado-CarmonaStéphanie Leroy-Lhez

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Methods Mentioned

BETA
irradiating

Software Mentioned

Photosens

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