Turnover of plasma free stearic and oleic acids in resting and exercising human subjects.

Metabolism: Clinical and Experimental
L Hagenfeldt, J Wahren

Abstract

Turnover rates and metabolism in the legs and the splanchnic region of free stearic and oleic acid have been studied in five healthy male volunteers at rest and during bicycle exercise. A continuous infusion of 14C-labeled stearic acid and tritiated oleic acid was given intravenously. At rest, the fractional turnover was the same for the two acids; the fractional leg uptakes were also similar, while fractional uptake in the splanchnic region was 80% higher for oleic than for stearic acid. The response to exercise differed between the two acids: the arterial concentration of stearic acid fell, its fractional turnover and fractional leg uptake became higher than for oleic acid, and its fractional uptake in the splanchnic region increased, while that of oleic acid remained unchanged. It is concluded (1) that stearic acid turnover in the postabsorptive state is similar to that of the main part of the FFA fraction and (2) that the decrease in stearic acid concentration during exercise can be explained by an increased removal in excess of that for other FFA.

References

Jul 1, 1975·Metabolism: Clinical and Experimental·L Hagenfeldt, J Wahren
Sep 1, 1972·The Journal of Clinical Investigation·L HagenfeldtL Räf
Nov 1, 1971·Clinical Science·L Jorfeldt, J Wahren
Mar 1, 1970·The Journal of Clinical Investigation·L V Basso, R J Havel
Jan 1, 1968·Scandinavian Journal of Clinical and Laboratory Investigation·L Hagenfeldt, J Wahren
Feb 1, 1966·Clinica Chimica Acta; International Journal of Clinical Chemistry·L Hagenfeldt
Nov 1, 1958·The Journal of Clinical Investigation·D S FREDRICKSON, R S GORDON
Apr 1, 1959·Proceedings of the Society for Experimental Biology and Medicine·R BLOMSTRANDE LINDER
Jul 1, 1961·The American Journal of Physiology·D T ARMSTRONGR C DE BODO
May 1, 1963·Proceedings of the Society for Experimental Biology and Medicine·C R FORDJ H MORRIS
Dec 1, 1962·The American Journal of Physiology·D L TROUT, E H ESTES
Dec 1, 1963·Metabolism: Clinical and Experimental·A CARLSTENL WERKOE
Mar 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·P KAPILOFFI L CHAIKOFF
Apr 1, 1965·Acta Physiologica Scandinavica·G GOERANSSON

❮ Previous
Next ❯

Citations

Apr 12, 2001·European Journal of Internal Medicine·P Yli-JamaJ I. Pedersen
Jan 31, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Jean Michel WeberGeorges Zwingelstein
Apr 1, 1987·Molecular and Biochemical Parasitology·D L LongworthP F Weller
Oct 1, 1979·The American Journal of Physiology·A W Bell, G E Thompson
Aug 1, 1979·Food and Cosmetics Toxicology·D L Opdyke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.