Twelve-Month Outcomes of Stand-Alone Excisional Goniotomy in Mild to Severe Glaucoma

Clinical Ophthalmology
Mohammed K ElMallahGabriel S Lazcano-Gomez

Abstract

To describe 12-month intraocular pressure (IOP) and medication use outcomes following excisional goniotomy (EG) as a stand-alone procedure in eyes with medically uncontrolled glaucoma. This was a retrospective analysis of data from surgeons at 8 centers (6 US, 2 Mexico). Eyes with glaucoma undergoing standalone EG with a specialized instrument (Kahook Dual Blade, New World Medical, Rancho Cucamonga, CA) for IOP reduction and followed for 12 months postoperatively were included. Data were collected preoperatively, intraoperatively, and 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. The primary outcome was reduction from baseline in IOP, and key secondary outcomes included IOP-lowering medication reduction as well as adverse events. A total of 42 eyes were analyzed, of which 36 (85.7%) had mild to severe primary open-angle glaucoma (POAG). Mean (standard error) IOP at baseline was 21.6 (0.8) mmHg, and mean number of medications used at baseline was 2.6 (0.2). At 3, 6, and 12 months postoperatively, mean IOP reductions from baseline were 4.6 mmHg (22.3%), 5.6 mmHg (27.7%), and 3.9 mmHg (19.3%) (p≤0.001 at each time point). At the same time points, mean medications reductions of 0.7 (25.8%), 0.9 (32.6%), and 0.3 (12.5%)...Continue Reading

References

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Aug 9, 2017·American Journal of Ophthalmology·Davinder S GroverBarbara Niksch
Oct 11, 2017·Journal of Cataract and Refractive Surgery·Michael D GreenwoodJohn P Berdahl
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Jan 1, 2018·Ophthalmology. Glaucoma·Erin G SieckLeonard K Seibold

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Citations

Dec 15, 2020·Current Opinion in Ophthalmology·Kateki Vinod, Steven J Gedde
Jul 24, 2021·Seminars in Ophthalmology·Faith A BirnbaumDavid Solá-Del Valle

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