Twenty-five year mortality of a community cohort with schizophrenia.

The British Journal of Psychiatry : the Journal of Mental Science
Steve BrownHazel Inskip

Abstract

People with schizophrenia have significantly raised mortality but we do not know how these mortality patterns in the UK have changed since the 1990s. To measure the 25-year mortality of people with schizophrenia with particular focus on changes over time. Prospective record linkage study of the mortality of a community cohort of 370 people with schizophrenia. The cohort had an all-cause standardised mortality ratio of 289 (95% CI 247-337). Most deaths were from the common causes seen in the general population. Unnatural deaths were concentrated in the first 5 years of follow-up. There was an indication that cardiovascular mortality may have increased relative to the general population (P = 0.053) over the course of the study. People with schizophrenia have a mortality risk that is two to three times that of the general population. Most of the extra deaths are from natural causes. The apparent increase in cardiovascular mortality relative to the general population should be of concern to anyone with an interest in mental health.

References

Oct 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·P Munk-Jørgensen, P B Mortensen
Apr 1, 1990·Acta Psychiatrica Scandinavica·P B Mortensen, K Juel
Jul 1, 1986·Archives of General Psychiatry·K S Kendler
Jan 1, 1984·The British Journal of Psychiatry : the Journal of Mental Science·J S GibbonsJ L Gibbons
Aug 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·P B Mortensen, K Juel
Mar 31, 1998·The British Journal of Psychiatry : the Journal of Mental Science·S Brown
Apr 16, 1998·The British Journal of Psychiatry : the Journal of Mental Science·H M InskipB Barraclough
Dec 16, 1998·The British Journal of Psychiatry : the Journal of Mental Science·E C Harris, B Barraclough
Jul 15, 1999·Psychological Medicine·S BrownC Thompson
Aug 19, 2000·BMJ : British Medical Journal·U OsbyP Sparén
Oct 19, 2000·Social Psychiatry and Psychiatric Epidemiology·D LawrenceT J Pinder
Oct 21, 2000·The British Journal of Psychiatry : the Journal of Mental Science·S BrownB Barraclough
Nov 2, 2001·The British Journal of Psychiatry : the Journal of Mental Science·V HansenE Arnesen
Apr 13, 2002·Schizophrenia Research·Raimo K R SalokangasAnna-Maija Koivisto
Dec 4, 2003·The British Journal of Psychiatry : the Journal of Mental Science·R G McCreadie, UNKNOWN Scottish Schizophrenia Lifestyle Group
May 28, 2005·Psychological Medicine·Hannele HeiläJouko Lönnqvist

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Citations

May 12, 2011·Social Psychiatry and Psychiatric Epidemiology·Steve Brown, Clemence Mitchell
Aug 31, 2012·European Archives of Psychiatry and Clinical Neuroscience·Stephan RuhrmannFrauke Schultz-Lutter
Mar 5, 2013·The Psychiatric Quarterly·Arno KerlingMarcel Sieberer
Dec 14, 2011·Psychological Medicine·R DuttaJ E Boydell
Sep 15, 2010·Current Opinion in Psychiatry·Thomas J Raedler
Jan 18, 2012·Current Opinion in Psychiatry·Thomas M LaursenMogens Vestergaard
Sep 25, 2012·The Australian Journal of Rural Health·Brenda HappellJanette Nankivell
Oct 15, 2010·Journal of Psychopharmacology·Hiram Joseph WildgustMike Beary
Oct 15, 2010·Journal of Psychopharmacology·Chris J BusheJari Haukka
Oct 15, 2010·Journal of Psychopharmacology·Hiram Joseph Wildgust, Mike Beary
Oct 15, 2010·Journal of Psychopharmacology·Richard HodgsonChris J Bushe
Sep 13, 2013·International Journal of Environmental Research and Public Health·Sharon Lawn, Jonathan Campion
Apr 9, 2013·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Helen Lester
Jun 13, 2012·The Primary Care Companion to CNS Disorders·David AshCherrie Galletly
Aug 21, 2013·Journal of Pharmacology & Pharmacotherapeutics·Rakesh K ChaddaMamta Sood
Dec 10, 2013·Annual Review of Clinical Psychology·Thomas Munk LaursenPreben Bo Mortensen
Feb 25, 2014·Social Psychiatry and Psychiatric Epidemiology·Anthony P Polednak
Oct 12, 2013·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jennifer W TideyEmily M H Xavier
Jan 22, 2013·Annual Review of Clinical Psychology·Kim T MueserJeffrey E Cassisi
Oct 12, 2011·BMC Psychiatry·Solomon TeferraLars Jacobsson
Oct 5, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Yana VinogradovaCatherine Penny
May 20, 2015·Issues in Mental Health Nursing·Brenda Happell, Chris Platania-Phung
Feb 8, 2014·Issues in Mental Health Nursing·Linda E RoseAnita Everett
Oct 13, 2012·International Review of Psychiatry·Ary GadelhaJair de Jesus Mari
Jul 1, 2010·Expert Review of Neurotherapeutics·Lawrence Maayan, Christoph U Correll

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