PMID: 8947297Nov 20, 1996Paper

Twenty-five years of HTLV type II follow-up with a possible case of tropical spastic paraparesis in the Kayapo, a Brazilian Indian tribe

AIDS Research and Human Retroviruses
F L BlackJ P Filho

Abstract

A longitudinal study, spanning 25 years and great demographic and cultural change, found a persistently high prevalence of human T-lymphotropic virus type II (HTLV-II) in the Xikrin Kayapo Indians of Brazil. More than 10% of the children continue to develop immune reactions to the virus in infancy, a sharp increase in seroprevalence occurs between ages 15 and 30 years, and prevalence in older woman still approaches 100%. This suggests that the major modes of transmission (breast milk and sexual activity) have not changed. The demonstration of stable maintenance of HTLV-II in one ethnic group makes migration theories of its dispersal more plausible. However, the infection may not be a negligible burden on population survival: at least 1 of 62 persons followed until age 40 years died of possible tropical spastic paraparesis (TSP).

References

Jul 1, 1992·The Journal of Infectious Diseases·E M MaloneyW A Blattner
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Sep 1, 1994·AIDS Research and Human Retroviruses·F L BlackD J Waters
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Citations

Jul 29, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mirna M BiglioneMaría I Berría
Apr 15, 1997·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·R B LalF Black
Apr 30, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·M Leon-PonteB J Poiesz
Jan 10, 2002·Journal of Medical Virology·Edimilson A SilvaAna Carolina P Vicente
Jul 6, 2004·Annals of Neurology·Abelardo Araujo, William W Hall
Jan 29, 2002·Revista Da Sociedade Brasileira De Medicina Tropical·R IshakM O Guimarães Ishak
Sep 16, 2003·Cadernos de saúde pública·Ricardo IshakMarluísa de Oliveira Guimarães Ishak
Apr 2, 2004·Revista Do Instituto De Medicina Tropical De São Paulo·Olinda MacêdoAlexandre C Linhares
Mar 31, 2004·Revista Da Sociedade Brasileira De Medicina Tropical·Denise Duizit ColinJosé Tavares-Neto

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