PMID: 9440385Jan 24, 1998Paper

Twenty-four-hour energy balance in Crohn disease patients: metabolic implications of steroid treatment

The American Journal of Clinical Nutrition
G MingroneG Gasbarrini

Abstract

Several hypotheses have been proposed to explain the nutritional deficiencies seen in Crohn disease patients, including inadequate food intake, decreased assimilation and increased loss of nutrients, and increased energy expenditure. To assess the effect of steroid therapy on body composition, energy expenditure, and fuel selection in Crohn disease, we compared 12 patients (6 men and 6 women) with biopsy-proven ileal Crohn disease with 11 healthy volunteers (6 men and 5 women). Five patients [Crohn's disease activity index (CDAI) = 98.4 +/- 3.78] took no medication and seven patients (CDAI = 283.9 +/- 22.5) were administered 29 +/- 18 mg prednisone/d. Body composition was evaluated by isotopic dilution and bioelectrical impedance analysis, and 24-h energy expenditure and basal metabolic rate were measured in a respiratory chamber. Fat-free mass was not significantly different among groups, whereas fat mass was lower in patients than in control subjects. Energy intake was higher in treated patients than in both untreated patients (P = 0.004) and control subjects (P = 0.005). Fecal losses were not significantly different between untreated patients and control subjects, but were higher (and proportional to the CDAI) in treated pat...Continue Reading

Citations

Dec 22, 1998·The American Journal of Gastroenterology·E CapristoG Gasbarrini
Jul 23, 2003·The American Journal of Gastroenterology·Jørgen JahnsenErling Aadland
Aug 20, 2008·Molecular Nutrition & Food Research·Benoît DupontJean-Marie Reimund
Jan 28, 2010·Journal of Clinical Biochemistry and Nutrition·Masaya SasakiAkira Andoh
Feb 16, 1999·The American Journal of Clinical Nutrition·G MingroneG Gasbarrini
Sep 12, 2000·Current Gastroenterology Reports·D G Kelly
Mar 13, 2002·Transplantation·Fabio M UlivieriBruno M Cesana
Aug 10, 2005·The American Journal of Clinical Nutrition·Jon M BurnhamMary B Leonard
May 15, 2008·Inflammatory Bowel Diseases·Stéphane M SchneiderXavier Hébuterne
Apr 14, 2000·Journal of the American College of Nutrition·G BenedettiG Gasbarrini
Nov 12, 2002·The American Journal of Gastroenterology·Rima Al-JaouniXavier Hébuterne
Mar 18, 2005·JPEN. Journal of Parenteral and Enteral Nutrition·Kathryn CormierPaul Pencharz
Jun 15, 2013·Alimentary Pharmacology & Therapeutics·R V BryantJ M Andrews
Jun 6, 2009·World Journal of Gastroenterology : WJG·Corina HartmanRaanan Shamir
May 14, 2011·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·K GerasimidisC A Edwards
May 8, 1999·Scandinavian Journal of Gastroenterology·E CapristoG Gasbarrini
Apr 2, 1999·Alimentary Pharmacology & Therapeutics·E CapristoG Gasbarrini
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Laurence KatznelsonAnne Klibanski
Aug 8, 2007·The American Journal of Gastroenterology·Catarina Sousa GuerreiroCarlos Nobre Leitão
May 29, 2015·Arquivos De Gastroenterologia·Maria Izabel Siqueira de AndradeAugusto César Barreto Neto
Mar 9, 2002·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·A BlainJ Cosnes
May 16, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·H LochsUNKNOWN ESPEN (European Society for Parenteral and Enteral Nutrition)
Jun 12, 2009·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·André Van GossumUNKNOWN ESPEN

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