Twenty-Year Trends in the American Heart Association Cardiovascular Health Score and Impact on Subclinical and Clinical Cardiovascular Disease: The Framingham Offspring Study

Journal of the American Heart Association
Danielle M EnserroVanessa Xanthakis

Abstract

Data on the temporal trends in ideal cardiovascular health (CVH) as well as on their association with subclinical/overt cardiovascular disease (CVD) and death are limited. This study included 3460 participants attending ≥1 of 4 consecutive exams of the Framingham Heart Study (1991-2008, mean age 55.4 years, CVH score ranged 0-14). We created 4 groups describing changes in CVH score between examination cycles 5 and 8, using first and last exams attended (high-high: starting CVH score ≥8, last score of ≥8, referent; high-low: ≥8 start and ≤7 last; low-high: ≤7 start and ≥8 last; and low-low: ≤7 start and ≤7 last) and related them to subclinical CVD cross-sectionally, and incident CVD and death. Fewer people have ideal CVH scores over the past 20 years (8.5% for 1991-1995, 5.9% for 2005-2008, P=0.002), because of decreases in those with ideal status of body mass index, blood glucose, and serum cholesterol levels (P<0.05 for all). The odds of subclinical disease and risk of CVD and death were higher for all compared with the high-high group (428 CVD and 367 death events, median follow-up 5.1 years, hazard ratios for CVD: 1.39, 1.73, 1.9 and death: 1.12, 1.57, 1.4 and odds ratios for subclinical disease: 1.61, 1.98, 2.86 for high-lo...Continue Reading

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Citations

Jan 22, 2020·Psychiatric Services : a Journal of the American Psychiatric Association·Peter P ZandiJ Raymond DePaulo
Jul 23, 2019·European Heart Journal. Quality of Care & Clinical Outcomes·Bamba GayeXavier Jouven
Jul 1, 2020·Circulation. Cardiovascular Quality and Outcomes·Joshua D BundyNorrina B Allen
Sep 12, 2020·Stroke; a Journal of Cerebral Circulation·Ayesha AhmedGoya Wannamethee
Sep 29, 2020·Journal of the American Heart Association·Bamba GayeXavier Jouven
Nov 7, 2018·JAMA : the Journal of the American Medical Association·Thomas T van SlotenJean-Philippe Empana
Jun 19, 2019·Statistics in Medicine·Danielle M EnserroRalph B D'Agostino
Nov 23, 2020·European Journal of Epidemiology·Louise BrunkwallPeter M Nilsson
Feb 25, 2021·European Journal of Preventive Cardiology·James M MuchiraLaura L Hayman
Mar 26, 2021·Journal of the American Heart Association·Joshua D BundyNorrina B Allen
Apr 4, 2021·Journal of Personalized Medicine·Jane A LeopoldElliott M Antman
May 18, 2021·Journal of the American Heart Association·Pil-Sung YangBoyoung Joung
Jun 1, 2021·Expert Review of Cardiovascular Therapy·Erin D Michos, Sadiya S Khan
Jul 3, 2021·Journal of Clinical Medicine·Jane A Leopold, Elliott M Antman
Jul 23, 2021·Scientific Reports·Jane A Leopold, Elliott M Antman
Jul 18, 2021·The American Journal of Medicine·Eric Y DingRobert J Goldberg
Jul 9, 2021·Journal of Primary Care & Community Health·Susan M DevarajAndrea M Kriska
Aug 31, 2021·American Heart Journal Plus : Cardiology Research and Practice·Natalie StokesJared W Magnani
Oct 16, 2021·BMC Cardiovascular Disorders·Jane A Leopold, Elliott M Antman

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