Twin pregnancies complicated by gestational diabetes mellitus: a single centre cohort study

Diabetic Medicine : a Journal of the British Diabetic Association
G K DinhamA W Shand

Abstract

In women with a twin pregnancy, to determine the incidence of, risk factors for and outcomes of women with gestational diabetes mellitus, and assess how these have changed with a change in gestational diabetes screening. Retrospective cohort study of women with a twin pregnancy attending an Australian tertiary hospital, 2002-2013. Information on gestational diabetes status, gestational diabetes risk factors and pregnancy outcomes was ascertained. Pregnancy outcomes included hypertensive disorders, twin birthweight centile and a composite adverse pregnancy outcome. Analysis was stratified pre/post screening protocol change (epoch 1: 2002-2009, epoch 2: 2010-2013) and by gestational diabetes status. Gestational diabetes was diagnosed in 86/982 (8.8%) women, increasing from 4.4% to 14.7% between epochs (P = 0.0001). The proportion of women with hypertensive disorders increased (11.7% vs. 13.4%, P = 0.009), but the proportion of infant's birthweight > 90th centile decreased (11.0% vs. 7.6%, P = 0.02) between epochs. Overall, 33.6% of women had ≥ 1 risk factors for gestational diabetes. Three-quarters (73.7%) of women overall had an adverse pregnancy outcome, with a slightly higher proportion in women with gestational diabetes compa...Continue Reading

References

Oct 18, 2002·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·C L RobertsD J Henderson-Smart
Jun 14, 2005·The New England Journal of Medicine·Caroline A CrowtherUNKNOWN Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
Jul 16, 2005·American Journal of Obstetrics and Gynecology·Sarah McDonaldArne Ohlsson
Oct 26, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·M BonomoA Morabito
May 8, 2008·The Journal of Clinical Endocrinology and Metabolism·Christopher D SaudekMayer B Davidson
May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Apr 3, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jose A Rauh-HainRavi Thadhani
Sep 29, 2009·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Charles S AlgertChristine L Roberts
Oct 3, 2009·The New England Journal of Medicine·Mark B LandonUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Mar 2, 2010·Diabetes Care·UNKNOWN International Association of Diabetes and Pregnancy Study Groups Consensus PanelMaria Ines Schmidt
Sep 17, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nieves L González GonzálezJosé L Bartha
May 16, 2014·Archives of Gynecology and Obstetrics·Rania OkbySheiner Eyal
Jun 14, 2014·Diabetic Medicine : a Journal of the British Diabetic Association·M A GuillénL F Pallardo
Dec 3, 2014·American Journal of Obstetrics and Gynecology·Andrei RebarberNathan S Fox

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Citations

Aug 23, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Teresinha SimõesIsaac Blickstein
Dec 7, 2017·Diabetes Care·Sara Ooi, Vincent W Wong
Jan 22, 2019·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Annabel C M SheehanThomas J Cade
Jan 13, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·R T McGrathS J Glastras

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