journal cover

Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes

The American Journal of Pathology

Aug 23, 2011

Chang Ohk SungSeok-Hyung Kim

Abstract

Stromal fibroblasts perform important roles in cancer development and progression. Overexpression of Twist1, a basic helix-loop-helix transcription factor, is often associated with aggressive behavior in many tumors. In this study, we investigated Twist1 expression patterns in gastric s...read more

Mentioned in this Paper

Pathologic Cytolysis
Spastic Paraplegia 3, Autosomal Dominant
PDGFRB wt Allele
Spindle
Alcohols
Gene Expression Regulation, Neoplastic
Subfamily lentivirinae
Hydrogen sulfite
Transfection
Phenol
27
Paper Details
References
  • References33
  • Citations29
1234
  • References33
  • Citations29
123

Feeds With Similar Papers

Penicillins

Penicillin is a group of antibiotics that can be administered intravenously or intramuscularly to treat bacterial infections caused by staphylococci and streptococci. While they are still widely used today, many bacteria have developed resistance to penicillin. Here is the latest research on penicillins.

CpG Sites

CpG sites are genomic loci where cytosine is followed by a guanine along its 5’ to 3’ direction. CpG sites are common in CpG islands and its methylation has been implicated in cancer, aging, and gene silencing. Here is the latest research.

Penicillins (ASM)

Penicillin is a group of antibiotics that can be administered intravenously or intramuscularly to treat bacterial infections caused by staphylococci and streptococci. While they are still widely used today, many bacteria have developed resistance to penicillin. Here is the latest research on penicillins.

Fibrosarcoma

Fibrosarcoma is a malignant soft tissue sarcoma that arises in fibroblasts and can metastasize both locally and distantly. Discover the latest research on Fibrosarcoma here.

DiGeorge Syndrome

DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a syndrome caused by the deletion of a small segment of chromosome 22. It is is characterized by cardiovascular, thymus and parathyroid defects and craniofacial anomalies. Discover the latest research on DiGeorge Syndrome here.

DNA Methylation

DNA methylation is an epigenetic mechanism of gene regulation, and dysregulation of DNA methylation has been associated with tumorigenesis. Discover the latest research on DNA methylation here.

Signal Transduction & Gene Expression (Keystone)

Tumor cells have their own unique signal transduction and gene expression control. Targeting these specific cellular mechanisms and genetic proflies of cancer cells is an area of therapeutic exploration for some cancers. Discover the latest research on this topic with this feed.

Chemokines & Chemokine Receptors

Chemokines are a subset of cytokines which induce chemotaxis in cells expressing chemokine receptors. Chemokines can be broadly categorized into two functional subgroups, homeostatic (basal expression in lymphoid tissues for surveillance purposes) or inflammatory (released during injury to recruit immune effector cells). Chemokine receptors are G-protein coupled receptors which, upon chemokine binding, induce calcium influx into the cell. Find the latest research on chemokines and chemokine receptors here.

Signal Transduction & Gene Expression (Keystone)

Tumor cells have their own unique signal transduction and gene expression control. Targeting these specific cellular mechanisms and genetic proflies of cancer cells is an area of therapeutic exploration for some cancers. Discover the latest research on this topic with this feed.

DNA Methylation (Keystone)

DNA methylation is an epigenetic mechanism of gene regulation, and dysregulation of DNA methylation has been associated with tumorigenesis. Discover the latest research on DNA methylation here.

Nucleolar Dynamics

The nucleolus is the site of ribosome biogenesis, making ribosomal subunits from proteins and ribosomal RNA. Discover the latest research on nucleolar dynamics here.

Lung Epithelial Progenitor Cells

Lung epithelial progenitor cells are controlled by many different signaling molecules and are key in the regeneration of proper lung function. The use of manipulating endogenous lung stem cells to treat lung disorders is an exciting and novel area of research. Discover the latest research on lung epithelial progenitor cells here.

Related Papers

Annals of Surgical Oncology

TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer

Annals of Surgical OncologyNovember 13, 2008
Fátima Valdés-MoraJuan Carlos Lacal
BMC Cancer

Twist expression promotes migration and invasion in hepatocellular carcinoma

BMC CancerJuly 21, 2009
Noriyuki MatsuoKazuhide Yamamoto
© 2020 Meta ULC. All rights reserved

Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes

The American Journal of Pathology

Aug 23, 2011

Chang Ohk SungSeok-Hyung Kim

PMID: 21854747

DOI: 10.1016/j.ajpath.2011.06.032

Abstract

Stromal fibroblasts perform important roles in cancer development and progression. Overexpression of Twist1, a basic helix-loop-helix transcription factor, is often associated with aggressive behavior in many tumors. In this study, we investigated Twist1 expression patterns in gastric s...read more

Mentioned in this Paper

Pathologic Cytolysis
Spastic Paraplegia 3, Autosomal Dominant
PDGFRB wt Allele
Spindle
Alcohols
Gene Expression Regulation, Neoplastic
Subfamily lentivirinae
Hydrogen sulfite
Transfection
Phenol
27

Feeds With Similar Papers

Penicillins

Penicillin is a group of antibiotics that can be administered intravenously or intramuscularly to treat bacterial infections caused by staphylococci and streptococci. While they are still widely used today, many bacteria have developed resistance to penicillin. Here is the latest research on penicillins.

Related Papers

Annals of Surgical Oncology

TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer

Annals of Surgical OncologyNovember 13, 2008
Fátima Valdés-MoraJuan Carlos Lacal
BMC Cancer

Twist expression promotes migration and invasion in hepatocellular carcinoma

BMC CancerJuly 21, 2009
Noriyuki MatsuoKazuhide Yamamoto
Paper Details
References
  • References33
  • Citations29
1234
  • References33
  • Citations29
123

Download from

Publisher
PubMed
/papers/twist1-is-up-regulated-in-gastric-cancer-associate/21854747