Two- and three-dimensional high-resolution imaging of the human oviduct with optical coherence tomography

Fertility and Sterility
J M HerrmannJ G Fujimoto

Abstract

To evaluate the feasibility of optical coherence tomography, a new method of micron-scale imaging, for high-resolution assessment of the oviduct. Optical coherence tomography is analogous to ultrasound except that it measures the backreflection of infrared light rather than acoustical waves. The ampulla of a human fallopian tube was imaged in vitro using optical coherence tomography. Images were generated in 2 and 3 dimensions. University. Samples were obtained from women who had undergone hysterectomy for leiomyomatosis. None The ability to perform imaging on a micron scale, which is a level of resolution higher than that of any currently available clinical technology. Two- and three-dimensional data sets of the reflectance of a human fallopian tube were acquired. A volume of 5 x 5 x 2.5 mm (length x width x depth) was scanned. The axial resolution was 11 microm, and the lateral resolution at the focus was 20 microm. The data sets showed detailed structures of the fallopian tube. Our ability to obtain micron-scale two- and three-dimensional images of an in vitro oviduct suggests that it may be possible to identify and surgically treat tubal causes of infertility.

References

Nov 22, 1991·Science·D HuangC A Puliafito
Jun 27, 1997·Science·G J TearneyJ G Fujimoto

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Citations

Mar 5, 2005·The Journal of Thoracic and Cardiovascular Surgery·N HannaM Brenner
Dec 12, 2012·Journal of Biomedical Optics·Mikhail KirillinNatalia Shakhova
Jul 21, 2004·Gastrointestinal Endoscopy Clinics of North America·John M Poneros
Aug 15, 2003·Gastrointestinal Endoscopy Clinics of North America·John M Poneros, Norman S Nishioka
Mar 26, 1999·The Journal of Surgical Research·S A BoppartJ G Fujimoto
May 4, 2004·Head & Neck·Liron PantanowitzJames L Connolly
Jul 21, 2017·Journal of Biomedical Optics·Wendy-Julie MadoreNicolas Godbout
May 27, 2016·Journal of Biomedical Optics·Raksha RaghunathanKirill V Larin
Dec 7, 2017·Journal of Biomedical Optics·Mikhail KirillinNatalia Shakhova
Oct 28, 1999·Current Opinion in Ophthalmology·C R Baumal
Jul 24, 2015·Biomedical Optics Express·Jason C BurtonIrina V Larina
May 6, 2002·Optics Express·Markus LaubscherRene Salathe

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