PMID: 6165007Feb 1, 1981Paper

Two allelic forms of mouse beta 2-microglobulin

Proceedings of the National Academy of Sciences of the United States of America
P J RobinsonK Sege

Abstract

Two allelic forms of mouse beta 2-microglobulin (beta 2m), the small polypeptide chain of H-2 histocompatibility antigens, have been identified. The two forms can be distinguished by NaDodSO4/polyacrylamide gel electrophoresis. All inbred mouse strains express a single beta 2m isotype. Mice heterozygous for beta 2m synthesize both forms, showing codominant expression of beta 2m alleles. In mice heterozygous for both H-2 and beta 3m, individual H-2 histocompatibility antigens associate with both beta 2m forms. Preliminary structural studies indicate differences in peptide composition between the two forms.

References

May 16, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·P W HallC V Vacca
Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·L TrägärdhP A Peterson
Aug 15, 1975·European Journal of Biochemistry·R A Laskey, A D Mills
Jan 1, 1974·Transplantation Reviews·N Tanigaki, D Pressman
Jan 1, 1974·Transplantation Reviews·L RaskP A Peterson
Apr 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·G D SnellD W Bailey
Jul 1, 1980·Immunogenetics·J MichaelsonE A Boyse

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Citations

Jan 1, 1981·Immunogenetics·P J RobinsonV Schirrmacher
Jan 1, 1983·Immunogenetics·J Michaelson
Jan 1, 1984·Immunogenetics·P J RobinsonK F Lindahl
Jul 1, 1982·Molecular Immunology·L GrafP J Robinson
Aug 1, 1983·Molecular Immunology·C Vincent, J P Revillard
Nov 20, 2003·Brain Research. Molecular Brain Research·Lotti TajouriLyn R Griffiths
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·D R CoxC J Epstein
Apr 1, 1987·Immunological Reviews·M WablC M Steinberg
Feb 1, 1982·European Journal of Immunology·J Langhorne, K F Lindahl

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