Two Case Presentations Infected by Trichosporon asahii and Treated with Voriconazole Successfully

Case Reports in Infectious Diseases
Hikmet Gulsah TanyildizGurses Sahin

Abstract

Background. Trichosporon asahii is an opportunistic fungus that causes infections in immunosuppressed patients. Neutropenia developing due to malignancies is an important risk factor for fungal infection. Case Report. We present two pediatric oncology cases successfully treated with voriconazole after T. asahii infection that is known to cause fatal sepsis and invasive fungal infection. Conclusion. There is no conclusive evidence that the antifungal agent voriconazole is effective in the neutropenic patients infected with Trichosporon asahii. Liposomal amphotericin B has also been reported to be inadequate for treatment. We believe that our patients were successfully treated and survived because the antifungal agents were started early and properly, although the infection can be fatal in up to 80% of cases despite treatment.

References

Jul 1, 1990·Journal of Clinical Microbiology·T J WalshP A Pizzo
May 10, 2002·Mycoses·Selma GökahmetoğluN Cetin
Jan 15, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S FournierJ M Molina
Aug 13, 2003·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Issei TokimatsuMasaru Nasu
May 14, 2005·Journal of Pediatric Hematology/oncology·Charalampos AntachopoulosEmmanuel Roilides
Apr 9, 2009·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Roseline ThibeaultPhilippe Ovetchkine
Nov 19, 2011·Transplant Infectious Disease : an Official Journal of the Transplantation Society·K HosokawaS Nakao
Oct 2, 2012·Indian Pediatrics·Vipin M VashishthaAmit Garg
Oct 10, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M C ArendrupUNKNOWN European Confederation of Medical Mycology

❮ Previous
Next ❯

Citations

Nov 2, 2016·Frontiers in Microbiology·João N de Almeida Júnior, Christophe Hennequin
May 17, 2017·Journal of the Pediatric Infectious Diseases Society·Catherine E FosterCarol J Baker

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Transplant Infectious Disease : an Official Journal of the Transplantation Society
E AbdalaM A Shikanai-Yasuda
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
C RiegerH Ostermann
The Cochrane Database of Systematic Reviews
K J JørgensenHelle Krogh Johansen
The Pediatric Infectious Disease Journal
Judith A Guzman-CottrillEllen G Chadwick
The Cochrane Database of Systematic Reviews
Karsten Juhl JørgensenHelle Krogh Johansen
© 2021 Meta ULC. All rights reserved