PMID: 8590369Jun 1, 1995Paper

Two cases of monozygotic twins, in each of which one fetus was prenatally diagnosed as having a heart anomaly

The Journal of Obstetrics and Gynaecology
H NegishiS Fujimoto

Abstract

In each of the 2 cases of monozygotic twins reported here, 1 of the fetuses was suspected, as a result of a prenatal ultrasonographic examination, of having congenital heart disease (CHD). One of twins (Case 1) had a hypoplastic left heart (HPLH), coarctation of the aorta (CoA), mitral stenosis (MS), and an atrial septal defect (ASD). Of the other twins (Case 2), 1 fetus had pure pulmonary atresia (PPA) and tricuspid regurgitation (TR). In Case 1, the fetus with CHD had a single umbilical artery, the other had otherwise. In Case 2, the fetus with CHD had a velamentous insertion and an accessory placenta, and the other fetus had a marginal insertion. These findings suggest that environmental factors such as blood flow, blood pressure and so on have a role in the etiology of CHD.

References

Jun 1, 1977·The American Journal of Cardiology·R C Anderson
Apr 1, 1989·American Journal of Obstetrics and Gynecology·N H Silverman
Jun 28, 1986·British Medical Journal·L D AllanM J Tynan
Sep 14, 1967·The New England Journal of Medicine·J J NoraD G McNamara
Mar 15, 1994·The American Journal of Cardiology·C K Phoon, C A Neill
Sep 1, 1949·Archives of Disease in Childhood·J E MORISON

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Citations

May 3, 2013·American Journal of Medical Genetics. Part a·Dianna NgJoseph T C Shieh
Jul 29, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Geoffrey A Machin
Feb 24, 2006·Fetal Diagnosis and Therapy·J HajduZ Papp
Jul 2, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R E AndrewsC C Lees

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