Two chimeric chromosomes of Streptomyces coelicolor A3(2) generated by single crossover of the wild-type chromosome and linear plasmid scp1

Journal of Bacteriology
Masayuki Yamasaki, H Kinashi

Abstract

Streptomyces coelicolor A3(2) strain 2106 carries a 1.85-Mb linear plasmid, SCP1'-cysD, in addition to a 7.2-Mb linear chromosome. Macrorestriction analysis indicated that both linear DNAs are hybrids of the wild-type chromosome and the linear plasmid SCP1 on each side. Nucleotide sequencing of the fusion junctions revealed no homology between the recombination regions. SCP1'-cysD contains an SCP1 telomere and a chromosomal telomere at each end and therefore does not have terminal inverted repeats. In addition, SCP1'-cysD could not be eliminated from strain 2106 by various mutagenic treatments. Thus, we concluded that both the 7.2-Mb chromosome and SCP1'-cysD are chimeric chromosomes generated by a single crossover of the wild-type chromosome and SCP1. This may be regarded as a model of chromosomal duplication in genome evolution.

References

Jul 1, 1976·Journal of General Microbiology·D A Hopwood, H M Wright
Apr 1, 1992·Journal of Bacteriology·J Zakrzewska-Czerwińska, H Schrempf
May 1, 1992·Journal of Bacteriology·M J Calcutt, F J Schmidt
Feb 1, 1991·Journal of Bacteriology·H Kinashi, M Shimaji-Murayama
Jul 1, 1969·Genetics·D A HopwoodH M Ferguson
Nov 1, 1995·Journal of Bacteriology·A LezhavaH Kinashi
Dec 1, 1993·Molecular Microbiology·Y S LinC W Chen
Nov 1, 1994·FEMS Microbiology Letters·P Leblond, B Decaris
Mar 1, 1993·Molecular Microbiology·C W ChenD A Hopwood
Mar 4, 1998·Molecular Microbiology·J N Volff, J Altenbuchner
Jun 6, 1998·Journal of Bacteriology·M RedenbachH Kinashi
Jun 5, 1998·Microbiology·Jutta KalkusHans G Schlegel
Jul 15, 1998·Molecular Microbiology·Z Qin, S N Cohen
Sep 11, 1999·Journal of Bacteriology·D KameokaH Kinashi
May 10, 2000·FEMS Microbiology Letters·J N Volff, J Altenbuchner
Jul 26, 2002·Molecular Microbiology·Zhongjun Qin, Stanley N Cohen
Sep 28, 2002·Trends in Genetics : TIG·Carton W ChenRalph Kirby
Jan 21, 2003·Journal of Bacteriology·Tetsuya UchidaHaruyasu Kinashi
Mar 8, 2003·Molecular Microbiology·Chih-Hung HuangCarton W Chen
Jul 2, 2003·Bioscience, Biotechnology, and Biochemistry·Shoichi InoueHaruyasu Kinashi
Sep 30, 1959·Annals of the New York Academy of Sciences·D A HOPWOOD
May 20, 2004·Journal of Bacteriology·Tetsuya UchidaHaruyasu Kinashi
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·C S Levings, R R Sederoff

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Citations

Nov 26, 2010·Journal of Industrial Microbiology & Biotechnology·Antonio StarcevicJohn Cullum
May 31, 2012·Journal of Industrial Microbiology & Biotechnology·Jurica ZuckoJohn Cullum
Sep 28, 2002·Trends in Genetics : TIG·Carton W ChenRalph Kirby
Oct 22, 2009·Natural Product Reports·Markus NettBradley S Moore
Jun 10, 2006·Annual Review of Genetics·David A Hopwood
Jun 15, 2011·Bioscience, Biotechnology, and Biochemistry·Yingjie YangHaruyasu Kinashi
Mar 21, 2007·Molecular Microbiology·Chih-Hung HuangCarton W Chen
Aug 7, 2013·FEMS Microbiology Letters·Yosi NinditaHaruyasu Kinashi
Mar 29, 2018·Scientific Reports·Grégory HoffPierre Leblond
Apr 20, 2018·The Journal of General and Applied Microbiology·Hung-Yin PanChih-Hung Huang
Sep 8, 2006·Molecular Biology and Evolution·Frédéric ChouletPierre Leblond
May 10, 2020·Scientific Reports·Abdoul-Razak TidjaniPierre Leblond
Nov 16, 2021·Microbial Genomics·Lis Algora-GallardoPaul R Herron

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