Mar 1, 1985

Two-day starvation does not alter the kinetics of blood--brain barrier transport and phosphorylation of glucose in rat brain

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
P D CraneW H Oldendorf


The blood-brain barrier (BBB) transport and brain phosphorylation of glucose were assessed in conscious rats subjected to 2 days of starvation. Although plasma glucose decreased, no significant changes in brain blood flow, BBB glucose transport, or 2-deoxy-D-glucose phosphorylation were observed. The data suggest that adaptive changes of brain glucose metabolism previously observed in starvation are located beyond the initial steps of brain entry and phosphorylation.

  • References21
  • Citations16


  • References21
  • Citations16


Mentioned in this Paper

Blood - Brain Barrier Anatomy
August Rats
Protein Phosphorylation
Glucose, (beta-D)-Isomer
Blood Flow
Glucose Metabolism
Cerebrovascular Circulation
Rat Brain

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