PMID: 5259766Jul 1, 1969Paper

Two deoxyribonuclease activities within purified vaccinia virus

Proceedings of the National Academy of Sciences of the United States of America
B G Pogo, S Dales

Abstract

Two DNases, both hydrolizing single-stranded DNA, were identified within highly purified particles of vaccinia virus. One of these, active optimally at pH 5.0, is an exonuclease and the other, most active at pH 7.8, is an endonuclease. These two activities were localized more specifically within the virus cores. Upon elimination of the envelopes, followed by removal of the lateral bodies of vaccinia, both DNases were activated, suggesting that a specific inhibitor of these enzymes may be present in the lateral bodies.

References

Sep 1, 1965·Virology·C Jungwirth, W K Joklik
Dec 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·A J Shatkin, J D Sipe
Jun 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·B R McAuslan, J R Kates
Jul 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·P H Gold, S Dales
Feb 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·R OkazakiA Sugino
May 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·M Oishi
Jul 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·J R Kates, B R McAuslan
Aug 1, 1968·Virology·S Dales, E H Mosbach
Jan 1, 1962·Cold Spring Harbor Symposia on Quantitative Biology·H HANAFUSA
Mar 1, 1964·Journal of Molecular Biology·N P SALZMANE D SEBRING
Apr 1, 1965·Analytical Biochemistry·E P GEIDUSCHEK, A DANIELS

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Citations

Jan 1, 1974·Archiv für die gesamte Virusforschung·S P Sahu, H C Minocha
Jun 1, 1974·Life Sciences·B R McAuslan
Sep 1, 1971·Virology·R RoblinR Dulbecco
Oct 1, 1975·Virology·J A HolowczakL Flores
Jan 1, 1979·Pharmacology & Therapeutics. Part B: General & Systematic Pharmacology·S Kit
Jun 1, 1971·Journal of Ultrastructure Research·J M Hyde, D Peters
Apr 21, 1971·Nature: New Biology·S MizutaniR T Wells
Aug 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·B G Pogo, S Dales
Jul 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·E Katz, B Moss
Mar 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·P Palese, G Koch
Nov 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·J R ParkhurstC Heidelberger
Jun 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B G Pogo, S Dales
Aug 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·C M Wei, B Moss
Apr 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·B G Pogo
Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·C F GaronB Moss
Aug 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·B G Pogo, C Friend
Nov 25, 1989·Nucleic Acids Research·S M Kerr, G L Smith
Nov 1, 1972·Antimicrobial Agents and Chemotherapy·S B HorwitzA P Grollman
Nov 1, 1974·Antimicrobial Agents and Chemotherapy·E KatzB Winer
Aug 1, 1973·The Journal of Clinical Investigation·R M LewisR S Schwartz
Jan 1, 1978·Archives of Virology·C D DenoyaJ L La Torre
Oct 5, 1974·Journal of Molecular Biology·P Geshelin, K I Berns
Aug 1, 1974·Virology·M TakeshitaA P Grollman
May 1, 1977·Virology·M Esteban, J A Holowczak
Oct 1, 1977·Virology·M EstebanJ A Holowczak
Jan 1, 1971·Virology·B G PogoD W Roberts
Dec 1, 1977·Virology·M EstebanJ A Holowczak
Apr 15, 1977·European Journal of Biochemistry·C Cajean-FeroldiJ Chantepie-Auray

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