PMID: 20622478Jul 14, 2010Paper

Two dogs with juvenile-onset skin diseases with involvement of extremities

The Journal of Veterinary Medical Science
Ji-Seon YoonToshiroh Iwasaki

Abstract

Two dogs of juvenile-onset skin diseases with involvement of extremities were examined by histopathological, immunohistochemical and ultrastructural analyses. Clinically, both cases showed alopecia and crusts on the face and extremities. Case 1 showed histopathology of dermo-epidermal separation. Ultrastructural analysis revealed that the clefts were recognized between hemidesmosomes and lamina densa. In case 2, histopathology showed follicular atrophy, vacuolar degeneration at lower epidermis and masseter muscle degeneration, without remarkable ultrastructural abnormalities in basement membrane zone of the skin. Thus, the findings in case 1 were compatible to those in junctional epidermolysis bullosa, while those in case 2 were compatible to dermatomyositis-like disease. Combination of histopathological and ultrastructural analyses was useful to distinguish the diseases in two dogs.

References

Feb 12, 1998·The British Journal of Dermatology·M NagataH Shimizu
Aug 5, 1998·Laboratory Investigation; a Journal of Technical Methods and Pathology·L PulkkinenJ Uitto
Mar 24, 2000·The Veterinary Record·E A FergusonR Cappello
Mar 2, 2005·The Journal of Investigative Dermatology·Annabelle CaptGuerrino Meneguzzi
Mar 14, 2008·Veterinary Dermatology·Jacquelyn M WahlKeith E Murphy

❮ Previous
Next ❯

Citations

May 7, 2014·Veterinary Dermatology·Francesca BrescianiMarco Pietra
Jul 13, 2019·Veterinary Dermatology·Katherine A BackelElizabeth A Mauldin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Related Papers

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
G X MedeirosS V D Simões
Journal of Comparative Pathology
G X MedeirosA S Borges
© 2021 Meta ULC. All rights reserved