Two fatalities associated with synthetic opioids: AH-7921 and MT-45

Forensic Science International : Synergy
Helena FelsAndreas Stoever

Abstract

In this study, two fatalities associated with the synthetic opioids AH-7921 and MT-45 are reported. Within the last few years, both compounds have emerged on the recreational drug market and are sold as "research chemicals" on the internet. In the first case, a 22-year-old woman was found dead in the bedroom of her apartment by two of her friends. A plastic bag labeled "AH-7921" was found in the apartment and the two friends stated that the deceased had consumed AH-7921 prior to her death. The woman was a known drug addict. In the second case, a 24-year-old man was found dead in his room by his mother. The deceased was sitting on a chair in front of his desk slumped over. Several bags of white powder labeled "MT-45", "Methoxmetamine" and "Methoxphenidine" were found in his room. Toxicological analyses of femoral blood, heart blood, liver, pericardial fluid, urine, vitreous humor and stomach content of the deceased were performed using liquid chromatography-quadrupole-time-of-flight mass spectrometry (LC-QTOF-MS). Time-of-flight mass spectrometry was carried out on an LC-Triple TOF 5600 system (AB Sciex) with electrospray ionization operated in positive mode. In the first case, additional hair analysis was performed by liquid ch...Continue Reading

Citations

Oct 30, 2018·Journal of Analytical Toxicology·Michael T Truver, Madeleine J Swortwood
Jan 29, 2019·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Gabriella RodaMichele Dei Cas
Sep 12, 2018·Brain Sciences·Paolo FrisoniMatteo Marti
Jul 18, 2017·Frontiers in Psychiatry·Jolanta B Zawilska
Jul 6, 2018·Frontiers in Pharmacology·Renata SoliminiRaffaele Giorgetti
Jul 16, 2019·Forensic Sciences Research·Inês TabarraEugenia Gallardo
Nov 13, 2018·Frontiers in Pharmacology·Marta ConcheiroGail Cooper
Jan 13, 2019·International Journal of Environmental Research and Public Health·Barbara LovrecicIcro Maremmani
May 7, 2018·Forensic Sciences Research·Olaf H Drummer
Apr 7, 2020·Archives of Toxicology·Dino Luethi, Matthias E Liechti
Jun 16, 2018·Proceedings·Kerry Anne RambaranSaeed K Alzghari
Jul 11, 2021·The Journal of Pharmacology and Experimental Therapeutics·Ellen A WalkerLi Fang

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