Two forms of repair of DNA in mammalian cells following irradiation

Biophysical Journal
M M Elkind, C Kamper

Abstract

When Chinese hamster cells are lysed on top of an alkaline sucrose gradient, in time a fairly discrete DNA-containing molecular species is released from an apparently more complex material. Small doses of X-radiation speed the resolution of this complex while large doses degrade the material released from it. Incubation after irradiation reverses both effects.

Citations

Jan 1, 1980·Radiation and Environmental Biophysics·F E Ahmed
Feb 1, 1972·Mutation Research·R B Painter, B R Young
May 1, 1973·Mutation Research·S N Buhl, J D Regan
Feb 1, 1979·Mechanisms of Ageing and Development·R W HartS P Modak
Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·J R SimpsonJ A Belli
Apr 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·J EpsteinJ B Little
Mar 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·D L DugleJ D Chapman
Jul 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·S M D'Ambrosio, R B Setlow
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C BorekW Troll
Oct 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J Friedman, E Huberman
Feb 1, 1977·Nucleic Acids Research·R B Sheridan, P C Huang
Jul 2, 1973·European Journal of Biochemistry·M Gross-BellardP Chambon
Dec 1, 1973·Environmental Health Perspectives·W G Flamm
Dec 18, 2007·Mutation Research·Peggy L Olive
Oct 19, 1976·Biochemistry·K W KohnC A Friedman
May 16, 1983·Biochemical and Biophysical Research Communications·M R MatternK W Kohn
May 1, 1974·Analytical Biochemistry·C S Lange, D F Liberman
Nov 1, 1976·Experimental Cell Research·R BasesK C Hsu
Jan 31, 1972·Biochemical and Biophysical Research Communications·M W McBurney, G F Whitmore
Oct 1, 1979·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·L K Mee, S J Adelstein
Mar 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·T Ono, S Okada
Nov 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·G Ahnström, K A Edvardsson
Nov 15, 1985·Cancer·M M Elkind
Nov 1, 1980·Photochemistry and Photobiology·F E Ahmed, R B Setlow
Apr 1, 1971·Photochemistry and Photobiology·E Ben-Hur, R Ben-Ishai
Oct 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·M M Elkind, C M Chang-Liu
May 1, 1978·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·L K MeeG Stein
Nov 1, 1988·International Journal of Radiation Biology·G Ahnström
Nov 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·S N BuhlJ D Regan
Jul 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·M M Elkind, C M Chang-Liu
Mar 1, 1973·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·G Ahnström, K Erixon
Nov 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·K T Wheeler, J D Linn
Aug 1, 1973·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·W Fox, M Fox
Jul 1, 1976·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·C W Dingman, T Kakunaga
May 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B Palcic, L D Skarsgard
Oct 1, 1974·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·H G ModigL Révész
Jan 1, 1971·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·A R Peterson, B W Fox
May 1, 1984·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·E Ben-Hur, M P Hagan
Dec 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·D L DugleA P Reuvers
Apr 1, 1973·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·M Fox, B W Fox
Jun 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·J A BelliJ A Brown
Jan 1, 1970·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B W Fox, M Fox
Nov 1, 1978·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·I P Hesslewood
Jun 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B Palcic, L D Skarsgard
May 1, 1981·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·E Ben-HurE Riklis
Sep 1, 1976·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·W F HohmanL D Skarsgard

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