PMID: 2118508Sep 1, 1990Paper

Two genes that regulate exopolysaccharide production in Rhizobium meliloti

Journal of Bacteriology
H J Zhan, J A Leigh

Abstract

We describe a new Rhizobium meliloti gene, exoX, that regulates the synthesis of the exopolysaccharide, succinoglycan, exoX resembled the psi gene of R. leguminosarum bv. phaseoli and the exoX gene of Rhizobium sp. strain NGR234 in its ability to inhibit exopolysaccharide synthesis when present in multiple copies, exoX did not appear to regulate the expression of exoP. The effect of exoX was counterbalanced by another R. meliloti gene, exoF. exoF is equivalent to Rhizobium sp. strain NGR234 exoY and resembles R. leguminosarum bv. phaseoli pss2 in its mutant phenotype and in portions of its deduced amino acid sequence. The effect of exoF on the succinoglycan-inhibiting activity of exoX depended on the relative copy numbers of the two genes. exoX-lacZ fusions manifested threefold-higher beta-galactosidase activities in exoF backgrounds than in the wild-type background. exoX mutants produced increased levels of succinoglycan. However, the exoF gene was required for succinoglycan synthesis even in an exoX mutant background. exoF did not affect the expression of exoP. Strains containing multicopy exoX formed non-nitrogen-fixing nodules on alfalfa that resembled nodules formed by exo mutants defective in succinoglycan synthesis. exoX...Continue Reading

References

Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D H Figurski, D R Helinski
Sep 1, 1988·Journal of Bacteriology·S LongG C Walker
Sep 1, 1986·Molecular & General Genetics : MGG·G F De VosE R Signer
Sep 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J A LeighG C Walker
Jul 1, 1984·Journal of Bacteriology·T M FinanE R Signer

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Citations

Aug 17, 2012·Journal of the Royal Society, Interface·Gary DorkenWilson C K Poon
Sep 1, 1990·Molecular Microbiology·J X Gray, B G Rolfe
Mar 29, 2002·Molecular Microbiology·Derek H Wells, Sharon R Long
Dec 17, 2011·International Journal of Molecular Sciences·Monika Janczarek
Feb 1, 1992·Molecular Microbiology·P NagpalS W Stanfield
Mar 2, 1999·Applied and Environmental Microbiology·X Wei, W D Bauer
Jul 31, 2007·Journal of Bacteriology·Eddie J CytrynMichael J Sadowsky
Jul 24, 2007·Journal of Bacteriology·Sarah A GlennJuan E González
Oct 31, 1998·Applied and Environmental Microbiology·M LiuG C Walker
Feb 18, 2006·Microbial Cell Factories·Anna SkorupskaJaroslaw Król
Oct 4, 2008·Genes & Development·Alexander Y Mitrophanov, Eduardo A Groisman

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