PMID: 11917249Mar 28, 2002Paper

Two HIV-1 epidemics in Argentina: different genetic subtypes associated with different risk groups

Journal of Acquired Immune Deficiency Syndromes : JAIDS
María M AvilaJean K Carr

Abstract

This study determined the risk behaviors and viral subtypes of HIV-1 found in 134 heterosexual HIV-seroprevalent maternity patients, 41 of their sexual partners (men who have sex with women [MSW]), and 95 homosexual men (men who have sex with men [MSM]) from Buenos Aires, Argentina. Peripheral blood mononuclear cells (PBMCs) were purified from blood and used for DNA extraction, amplification, and genotyping by the envelope heteroduplex mobility assay (env HMA). Most of the women had been infected by having sex with an already infected partner (84%), whereas most of the male partners had been infected via drug use (76%). Both the patients and their sexual partners were poorly educated, only 30% having completed secondary school. The MSM study subjects, however, were significantly better educated and had a lower prevalence of injecting drug use.Env HMA subtype F was found in 77% (103 of 134) of the maternity patients, with similar rates in their partners (73%). Most of the remaining samples were env subtype B. All but one of the couples was concordant in subtype. In the MSM risk group, however, only 10% were env HMA subtype F. Ninety percent of the MSM samples were subtype B. There are at least two independent epidemics of HIV-1 ...Continue Reading

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Citations

Oct 18, 2005·Current Infectious Disease Reports·Gustavo H Kijak, Francine E McCutchan
Aug 19, 2007·Retrovirology·María A PandoMaría M Avila
Apr 24, 2009·Retrovirology·Monick L GuimarãesGonzalo Bello
Oct 6, 2010·Virology Journal·Cristian De CandiaMauricio Carobene
Aug 10, 2011·Virology Journal·Guadalupe AndreaniLiliana Martínez Peralta
Mar 13, 2009·PloS One·Yuka NadaiJean K Carr
Aug 20, 2015·Journal of Medical Virology·Yinle QiChiyu Zhang
Sep 3, 2013·Journal of Virological Methods·Raj Shankarappa, James I Mullins
Dec 19, 2002·AIDS Research and Human Retroviruses·Jesse HierholzerJean K Carr
Apr 21, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Alex EspinosaMercedes Weissenbacher
Aug 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Silvia M MontanoUNKNOWN South American HIV Molecular Surveillance Working Group
Oct 27, 2007·AIDS Research and Human Retroviruses·Dario A DilerniaManuel Gómez-Carrillo
Jan 19, 2008·Journal of Medical Microbiology·Maria A PandoMaria M Avila
Jul 1, 2006·Current Opinion in HIV and AIDS·Jean K Carr
Dec 7, 2006·AIDS Research and Human Retroviruses·Manuel Gomez-CarrilloUNKNOWN NISDI Perinatal Study Group
Sep 10, 2009·Revista Do Instituto De Medicina Tropical De São Paulo·Cláudia Fontoura DiasLuis Fernando Brigido
Jan 15, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Mauricio Guillermo CarobeneHoracio Salomón
Feb 17, 2010·AIDS Research and Human Retroviruses·Sodsai TovanabutraFrancine M McCutchan
Mar 31, 2009·AIDS Research and Human Retroviruses·Dora RuchanskyCecilio Lopez-Galindez
Mar 31, 2009·AIDS Research and Human Retroviruses·Héctor R RangelFlor H Pujol
Aug 3, 2005·AIDS Research and Human Retroviruses·Luis F M BrígidoRosangela Rodrigues
Aug 17, 2006·AIDS Research and Human Retroviruses·Magdi Darwish SaadJean Kirkland Carr
Jul 1, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Moira VignolesMercedes Weissenbacher
Aug 13, 2011·Journal of the International AIDS Society·M Eugenia SocíasUNKNOWN Grupo Argentino de Seroconversión Study Group

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