Two hundred intrauterine exchange transfusions in severe blood incompatibilities

American Journal of Obstetrics and Gynecology
M H PoissonnierJ Huchet

Abstract

Two hundred intrauterine exchange transfusions were performed under local anesthesia in 107 cases of blood incompatibilities (60 fetuses with severe anemia and 47 with hydrops). Under sonographic guidance, depending on fetal and placental position, an optimal puncturing site was selected along the umbilical vein: placental insertion, fetal insertion, or fetal intraabdominal segment. Tests were immediately performed to confirm fetal origin of blood obtained and estimate hemoglobin level. Blood used for exchange transfusion was compatible with maternal blood and had a hematocrit value of 75%. Exchange transfusion was continued until a hemoglobin level of 16 gm/dl was reached. This procedure was first associated with intraperitoneal transfusions and was subsequently used independently once a month to maintain an adequate hemoglobin level. In 4 fetuses with hydrops, antenatal regression of this sign was observed in 33 cases (70.2%). Overall outcome of 107 fetuses after exchanges was 84 living neonates (78.5%), 15 deaths in utero, and eight neonatal deaths. The survival rate was 91.6% for fetuses without hydrops and 61.7% for those with hydrops. The advantage of exchange transfusion appears to be rapid and efficient correction of an...Continue Reading

References

Dec 1, 1987·American Journal of Obstetrics and Gynecology·M L SocolR E Sabbagha
Aug 1, 1988·British Journal of Obstetrics and Gynaecology·I Z MacKenzieJ F Ferguson
Jan 1, 1986·Fetal Therapy·J T Queenan
Oct 1, 1988·American Journal of Obstetrics and Gynecology·V A BarssP M Doubilet
Apr 1, 1988·American Journal of Obstetrics and Gynecology·R L BerkowitzH H Bernstein
Mar 1, 1986·American Journal of Obstetrics and Gynecology·R L BerkowitzF A Chervenak
May 29, 1986·The New England Journal of Medicine·P A GrannumJ C Hobbins
Nov 15, 1985·American Journal of Obstetrics and Gynecology·F DaffosF Forestier
Nov 15, 1984·American Journal of Obstetrics and Gynecology·C H RodeckJ R Kemp
Apr 1, 1981·American Journal of Obstetrics and Gynecology·F D FrigolettoN T Griscom

❮ Previous
Next ❯

Citations

Jan 4, 1991·Klinische Wochenschrift·W Sterniste, A Rosen
Jan 1, 1994·Archives of Gynecology and Obstetrics·B PlöckingerG Bernaschek
Aug 1, 1995·Obstetrics and Gynecology·J YankowitzJ C Murray
Jul 1, 1996·Obstetrics and Gynecology·B Schumacher, K J Moise
Aug 26, 1993·The New England Journal of Medicine·P R BennettJ P Cartron
Dec 3, 2010·BMC Pregnancy and Childbirth·Esther P VerduinAnneke Brand
Dec 1, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·R D ChristensenE Henry
Apr 1, 1990·American Journal of Obstetrics and Gynecology·C R HarmanS M Menticoglou
Oct 2, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Janet Brennand, Alan Cameron
Mar 1, 1991·Blood Reviews·Y Tannirandorn, C H Rodeck
Jan 1, 1995·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·C Le Van KimJ P Cartron
Apr 16, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Lucie GuilbaudVéronique Houfflin-Debarge
Feb 24, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·K GutensohnT J Legler
Jun 27, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C GarabedianV Houfflin-Debarge
Jul 6, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C GarabedianV Houfflin-Debarge
Mar 3, 2012·American Journal of Obstetrics and Gynecology·Eveline P De JongEnrico Lopriore
May 1, 1997·American Journal of Obstetrics and Gynecology·J YankowitzC P Weiner
Sep 1, 1992·Baillière's Clinical Obstetrics and Gynaecology·G M Jackson, J R Scott
May 1, 1993·The Australian & New Zealand Journal of Obstetrics & Gynaecology·L W DoyleE A Kelly
May 1, 1994·The Australian & New Zealand Journal of Obstetrics & Gynaecology·A J SampsonH Robinson
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Jodie M DoddInge L van Kamp
Sep 4, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Joohee LeeHeehwa Choi
Feb 12, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Shaimaa AbdelshafiAhmad Elsheikhah
Mar 2, 1992·The Medical Journal of Australia·S E Meagher, N M Fisk

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.