PMID: 11607566Aug 1, 1995Paper

Two inducers of plant defense responses, 2,6-dichloroisonicotinec acid and salicylic acid, inhibit catalase activity in tobacco

Proceedings of the National Academy of Sciences of the United States of America
U ConrathD F Klessig

Abstract

2,6-Dichloroisonicotinic acid (INA) and salicylic acid (SA) are potent inducers of plant defense responses including the synthesis of pathogenesis-related (PR) proteins and the development of enhanced disease resistance. A soluble SA-binding protein has been purified from tobacco with an affinity and specificity of binding that suggest it is a SA receptor. Recently, this protein has been shown to be a catalase whose enzymatic activity is inhibited by SA binding. We have proposed that the resulting increase in intracellular levels of reactive oxygen species plays a role in the induction of defense responses such as PR protein gene expression. Here we report that INA, like SA, binds the SA-binding protein/catalase and inhibits its enzymatic activity. In fact, the dose-response curves for inhibition of catalase by these two compounds are similar. Furthermore, the ability of both INA analogues and SA derivatives to bind and inhibit tobacco catalase correlates with their biological activity to induce PR-1 gene expression and enhance resistance to tobacco mosaic virus. Comparison of the structures of INA, SA, and their analogues reveals several common features that appear to be important for biological activity. Thus, these results n...Continue Reading

References

Mar 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·A J EnyediI Raskin
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·H N Kirkman, G F Gaetani
Dec 1, 1994·Plant Molecular Biology·D F Klessig, J Malamy
Oct 1, 1993·The Plant Journal : for Cell and Molecular Biology·J HennigD F Klessig
Oct 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·Z ChenD F Klessig
Sep 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·Z Chen, D F Klessig
Sep 1, 1994·Trends in Cell Biology·D A Dempsey, D F Klessig

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Citations

Jan 15, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Qin XuXiaoya Hu
Jan 1, 1997·Free Radical Biology & Medicine·C R McClung
Feb 1, 1996·Current Opinion in Immunology·K ShirasuC Lamb
May 7, 2002·Trends in Plant Science·Uwe ConrathBrigitte Mauch-Mani
Oct 21, 2004·The Plant Journal : for Cell and Molecular Biology·O Thulke, U Conrath
Sep 30, 2010·Proceedings of the National Academy of Sciences of the United States of America·Kevin A FordMary C Wildermuth
Aug 1, 1995·Proceedings of the National Academy of Sciences of the United States of America·X Dong
Jun 14, 2013·Omics : a Journal of Integrative Biology·Aïcha BelkadhiWided Chaïbi
Jun 9, 2007·Molecular Plant-microbe Interactions : MPMI·Zenaida V MagbanuaDawn S Luthe
Jun 13, 2002·Molecular Plant-microbe Interactions : MPMI·Shane L MurrayGary J Loake
Feb 13, 2003·Molecular Plant-microbe Interactions : MPMI·Paulina C van SpronsenKees J M Boot
Aug 9, 2003·Molecular Plant-microbe Interactions : MPMI·John J GrantGary J Loake
Jun 1, 1997·Annual Review of Plant Physiology and Plant Molecular Biology·Chris Lamb, Richard A. Dixon
May 15, 2002·Bioscience, Biotechnology, and Biochemistry·Tomonori KawanoFrédéric Lapeyrie
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·J DurnerD F Klessig
Dec 10, 1996·Proceedings of the National Academy of Sciences of the United States of America·Y Yang, D F Klessig
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·D F KlessigH Silva
May 17, 2001·Proceedings of the National Academy of Sciences of the United States of America·Z XieZ Chen
Jan 9, 2009·Bioscience, Biotechnology, and Biochemistry·Jyun-Ichi EndoOsamu Tanaka
Jun 23, 2006·The Plant Journal : for Cell and Molecular Biology·Christian OchsenbeinKlaus Apel
Nov 27, 2015·BMC Plant Biology·Jana Viola SchillingJochen Büchs
Dec 3, 2014·Plant Science : an International Journal of Experimental Plant Biology·Dhirendra Kumar
Jan 8, 2015·Frontiers in Plant Science·Sandra FonsecaAndrea Chini
Feb 13, 2015·Frontiers in Plant Science·Yasemin Bektas, Thomas Eulgem
Jun 1, 2016·Frontiers in Plant Science·Keren Martínez-AguilarRaúl Alvarez-Venegas

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