Two new phenolic glucosides from Lagerstroemia speciosa

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Janggyoo ChoiKee Dong Yoon

Abstract

Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC50 values of 69.5-83.3 μM.

References

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Citations

Sep 28, 2015·Bioorganic & Medicinal Chemistry Letters·Roshan R KulkarniMinKyun Na
Mar 13, 2020·Journal of Asian Natural Products Research·Fang ChenPeng Wu
Oct 15, 2021·Journal of Asian Natural Products Research·Lu FuZhong-Mei Zou

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Methods Mentioned

BETA
column chromatography

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