Two new triterpenoid fatty acid esters from Schefflera barteri Harms (Araliaceae)§.

Natural Product Research
Judith Flore T MbougniaNorbert Sewald

Abstract

Two new fatty acid esters of triterpenoids (1-2) together with eleven known compounds (3-13) were obtained after investigation of the CH2Cl2-MeOH (1:1) crude extract from the leaves of Schefflera barteri Harms. All these compounds (1-13) were isolated for the first time from this plant among which compounds 3, 4, 6 and 9-13 were also isolated from the genus Schefflera for the first time. The structures of the isolated compounds were elucidated by analyses of their spectroscopic data (1D and 2D NMR, and MS). The antibacterial and cytotoxic activities of crude extracts, fractions and compounds (1, 2, 5, 6, 8 and 9) were investigated against both Gram-negative and Gram-positive bacteria strains as well as on human cervix carcinoma and colon adenocarcinoma cancer cell lines, respectively. They showed weak to significant activity towards the strains and malignant cells used.

References

Feb 1, 1981·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A GoldinV T Devita
Jan 12, 2000·Planta medica·W SchühlyO Sticher
Sep 29, 2001·Journal of Natural Products·T TanakaM Ishibashi
Sep 27, 2003·Journal of Natural Products·Leon A TapondjouKyung-Tae Lee
Jan 7, 2005·Chemical & Pharmaceutical Bulletin·Parinuch ChumkaewKan Chantrapromma
Sep 23, 2010·The Journal of Organic Chemistry·Benedikt SammetNorbert Sewald
Feb 22, 2012·Journal of Natural Medicines·Siti SusantiHirosuke Oku
May 16, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Takashi KikuchiReiko Tanaka
Aug 9, 2013·Planta medica·Chun WuYao-Lan Li
Feb 5, 2015·Natural Product Research·Tan Phat NguyenTrong Dat Bui
Apr 19, 2015·BMC Complementary and Alternative Medicine·Serge Secco AtsafackRosalie Annie Ngono Ngane
Nov 2, 2016·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Pierre MkoungaAugustin E Nkengfack
Nov 10, 2017·Journal of Natural Products·Lía S Valencia-ChanSergio R Peraza-Sánchez
May 30, 2019·Natural Product Research·Yi LinHanli Ruan
Jun 30, 2019·Natural Product Research·Alfred Ngenge TamfuFarzana Shaheen
Oct 5, 2019·Natural Product Research·Gaiëlle SonfackPierre Tane

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