Two new triterpenoid saponins from Gymnema sylvestre

Journal of Integrative Plant Biology
Xu-Min ZhuMing-Kui Wang

Abstract

Two new oleanane-type triterpenoid saponins, gymnemoside-W1 and W2, together with seven known compounds were isolated from the leaves of Gymnema sylvestre R. Br. By means of spectral and chemical analysis, the structures of the new compounds were elucidated as 16 beta-hydroxyl olean-12-en-3-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl]-28-O-beta-D-glucopyranoside(1) and 16 beta,21 beta,28-trihydroxyl-olean-12-ene-3-O-glucoronopyranoside (2). The EtOH/H(2)O extracts of this plant were shown to be able to inhibit glucose absorption in rats.

Citations

Jun 6, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Zhijun WangPatrick Chan
Jun 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·Staci P CohenNael A McCarty
Apr 16, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Ken YasukawaYasuhito Nobushi
Dec 7, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Giovanni Di FabioArmando Zarrelli
Jul 24, 2014·Phytochemistry·Suphongphan SrisurichanSurachai Pornpakakul
Dec 22, 2009·Natural Product Reports·Joseph D Connolly, Robert A Hill
Jun 3, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Phan Van KiemSeung Hyun Kim
Sep 14, 2019·Phytotherapy Research : PTR·Altaf Al-RomaiyanPeter Jones

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