PMID: 9638730Jun 25, 1998Paper

Two patients with isoniazid-induced photosensitive lichenoid eruptions confirmed by photopatch test

Photodermatology, Photoimmunology & Photomedicine
A Y Lee, S Y Jung

Abstract

Causative agents of drug eruptions are frequently unknown, and skin tests with candidate drugs would be useful before systemic challenge. It remains to be clarified how phostosentive lichenoid drug eruptions are induced, but allergy, including delayed type allergy, has been suggested. Two patients who had taken anti-tuberculous drugs developed a lichenoid drug eruption, primarily on sun-exposed skin. Patch and photopatch tests were performed with each of the ingested drugs (10% in petrolatum). Photopatch tests to isoniazid (INH) were positive. These were confirmed by oral challenge followed by irradiation with UVA. In conclusion, photopatch tests facilitated identification of the causative drug in two patients with photosensitive lichenoid eruptions to INH.

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Citations

Aug 23, 2002·Contact Dermatitis·R S L A BakkumH B Thio
Mar 21, 2002·International Journal of Dermatology·U TursenD Dusmez
Nov 5, 2011·Asia Pacific Allergy·Bernard Yu-Hor Thong
Sep 18, 2016·Clinics in Dermatology·Ana Filipe MonteiroCésar Martins
Jul 31, 2010·International Journal of Dentistry·Pratanporn ArirachakaranKobkan Thongprasom
Aug 7, 2014·Asia Pacific Allergy·Bernard Yu-Hor ThongHiok-Hee Chng
Mar 6, 2009·International Journal of Dermatology·Michelle H CollazoLuz D Figueroa
Apr 2, 2010·Allergy, Asthma & Immunology Research·Bernard Yu-Hor Thong
Apr 20, 2012·Expert Review of Anti-infective Therapy·Rannakoe J Lehloenya, Keertan Dheda
Mar 20, 2019·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Kim M BlakelyCheryl F Rosen
Sep 2, 2011·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Aaron M Drucker, Cheryl F Rosen
Jan 17, 2002·The Annals of Pharmacotherapy·A Y LeeY G Kim

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