PMID: 6169803Jan 1, 1981Paper

Two populations with multiple sclerosis. Clinical and demographic characteristics

Journal of Neurology
B VisscherJ Dudley

Abstract

Cross-sectional data from 1,793 cases of definite or probable multiple sclerosis (MS) identified in an extensive population survey in King and Pierce (K-P) Counties, Washington and Los Angeles (LA) County, California, were analyzed. Compared to the U.S. population as a whole, patients were more likely to be divorced and to have more years of schooling. The prevalence of MS was higher for females, and for northern-born, regardless of sex. Reconstructed age-, sex-specific incidence rate estimates for natives of the two areas showed a much higher peak annual incidence occurring in an older age group in K-P than in LA. Earliest symptoms in both areas were numbness in the legs, double vision, and loss of vision in one or both eyes. Weakness in arms, speech difficulties, and urinary incontinence tended to be late symptoms. The overall assessment of disability levels showed more than half of the patients to be fully ambulatory at the time of the first interview, with a somewhat higher proportion of each sex severely disabled in California. The ages of onset tended to be younger in LA than in K-P. The earlier onset of disease and the higher proportion of patients with high disability in Los Angeles County suggest that the course of dis...Continue Reading

References

Nov 1, 1978·American Journal of Epidemiology·R DetelsA H Coulson
Dec 1, 1977·American Journal of Epidemiology·B R VisscherJ P Dudley
Aug 1, 1973·Archives of Neurology·U LeibowitzM Alter
Mar 1, 1969·Brain : a Journal of Neurology·U LeibowitzM Alter
Jan 1, 1961·Acta Psychiatrica Scandinavica·K Hyllested
Mar 31, 1965·Annals of the New York Academy of Sciences·H J BAUERW WINKLER

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Citations

Jan 1, 1990·The Science of the Total Environment·G W Lowis
Sep 11, 1992·The Science of the Total Environment·G W Lowis
Apr 10, 2003·Annals of Epidemiology·Ya-Ping JinHans Link
Dec 1, 1996·Acta Neurologica Scandinavica·N Zilber, E Kahana
Sep 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·S R HammondD R English
Apr 1, 1995·Multiple Sclerosis : Clinical and Laboratory Research·L M Nelson, D W Anderson

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