Two predictors of postictal generalized EEG suppression: Tonic phase duration and postictal immobility period

Seizure : the Journal of the British Epilepsy Association
Marjan AsadollahiKurosh Gharagozli

Abstract

To determine the effect of different seizure characteristics on the occurrence of postictal generalized EEG suppression (PGES). PGES is considered as a potential risk factor of sudden unexpected death in epilepsy (SUDEP) by several studies. In this retrospective cross-sectional study, episodes of generalized convulsive seizures (GCS) were reviewed in regard to state at seizure-onset, the seizure and tonic phase durations, postictal immobility (PI) duration and whether the patient received oxygen (O2) mask during the post-ictal phase. Moreover, the presence and duration of PGES was determined for each seizure. Among 98 episodes of GCSs, 56 (57.1%) had PGES and 42 (42.9%) did not have PGES. The mean seizure duration for attacks with and without PGES was 106.62 ± 97.04 and 104.85 ± 91.81 s, respectively (P > 0.05). The tonic phase duration was significantly longer in PGES positive compared to PGES negative seizures (4.25 ± 3.17 s vs. 2.82 ± 3.58 s, P < 0.05). Early O2 mask administration and state of wakefulness at seizure-onset did not show any significant correlation with the presence of PGES (P > 0.05). Seizures with PGES had higher PI duration than those without PGES (156.24 s vs. 124.73 s) (P < 0.05). Interestingly, in seizur...Continue Reading

References

Jan 6, 2006·Epilepsia·Michael R SperlingMichael J O'Connor
Mar 29, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·B N McLean, S Wimalaratna
May 28, 2008·Epilepsia·Fred A Lado, Solomon L Moshé
Jan 10, 2009·Epilepsy & Behavior : E&B·John R Hughes
Jun 6, 2009·Epilepsia·Stephan U SchueleRichard C Burgess
Oct 1, 2010·Annals of Neurology·Samden D LhatooJonathan M Bird
May 17, 2011·Epilepsy & Behavior : E&B·Rainer SurgesJosemir W Sander
Jul 9, 2011·Lancet·Simon Shorvon, Torbjorn Tomson
Nov 5, 2011·Epilepsia·Mira SemmelrochLina Nashef
Dec 24, 2011·Epilepsia·Lina NashefTorbjörn Tomson
Apr 10, 2015·Science Translational Medicine·Isamu Aiba, Jeffrey L Noebels
Sep 4, 2015·Neurology·Veriano AlexandreUNKNOWN REPO2MSE study group

❮ Previous
Next ❯

Citations

May 13, 2020·Epilepsia·Julia C M PottkämperMichel J A M van Putten
Jun 11, 2020·Epilepsia·Sándor BeniczkyPhilippe Ryvlin
May 28, 2020·Epilepsia·Elisa BrunoUNKNOWN RADAR-CNS Consortium
Feb 6, 2020·Frontiers in Molecular Neuroscience·Jingjing FanQun Wang
Apr 20, 2021·Medical Hypotheses·A RabinovitchD Braunstein
May 29, 2021·Frontiers in Neurology·Xiuhe ZhaoNuria Lacuey
Aug 6, 2021·Epilepsia Open·Julia C M PottkämperMichel J A M van Putten

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.