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Two routes to functional adaptation: Tibetan and Andean high-altitude natives

Proceedings of the National Academy of Sciences of the United States of America

May 15, 2007

Cynthia M Beall

Abstract

Populations native to the Tibetan and Andean Plateaus are descended from colonizers who arrived perhaps 25,000 and 11,000 years ago, respectively. Both have been exposed to the opportunity for natural selection for traits that offset the unavoidable environmental stress of severe lifelo...read more

Mentioned in this Paper

Metabolic Process, Cellular
Dioxygen
Physiological Stress
IMC-11F8 monoclonal antibody
Environment
Candidate Disease Gene
Molecular Oxygen Saturation
Oxygen Saturation Measurement
High Altitude Pulmonary Edema
Anoxemia
12
1
1
386
4
Paper Details
References
  • References38
  • Citations214
1234
  • References38
  • Citations214
12345...

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Two routes to functional adaptation: Tibetan and Andean high-altitude natives

Proceedings of the National Academy of Sciences of the United States of America

May 15, 2007

Cynthia M Beall

PMID: 17494744

DOI: 10.1073/pnas.0701985104

Abstract

Populations native to the Tibetan and Andean Plateaus are descended from colonizers who arrived perhaps 25,000 and 11,000 years ago, respectively. Both have been exposed to the opportunity for natural selection for traits that offset the unavoidable environmental stress of severe lifelo...read more

Mentioned in this Paper

Metabolic Process, Cellular
Dioxygen
Physiological Stress
IMC-11F8 monoclonal antibody
Environment
Candidate Disease Gene
Molecular Oxygen Saturation
Oxygen Saturation Measurement
High Altitude Pulmonary Edema
Anoxemia
12
1
1
386
4

Feeds With Similar Papers

Hypoxia

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Here is the latest research.

Microbial ecology, genetics and evolution

Microbes are microscopic organisms which may exist in a unicellular or colony form. Here is the latest research on their genetic makeup, their relationship with one another and the environment, and their evolution.

Related Papers

Science

Genetic evidence for high-altitude adaptation in Tibet

ScienceMay 15, 2010
Tatum S SimonsonRiLi Ge
Proceedings of the National Academy of Sciences of the United States of America

An Ethiopian pattern of human adaptation to high-altitude hypoxia

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 10, 2002
Cynthia M BeallK P Strohl
Paper Details
References
  • References38
  • Citations214
1234
  • References38
  • Citations214
12345...

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