Two-stage transvaginal cervical length screening for preterm birth in twin pregnancies

Journal of Perinatal Medicine
Carolina HofmeisterM Zugaib

Abstract

To compare cervical length (CL) at 18-21 and 22-25 weeks' gestation in twin pregnancies in prediction of spontaneous preterm delivery and to examine cervical shortening. Retrospective cohort study of CL measured at 18-21 and 22-25 weeks' gestation in twin pregnancies. Receiver operating characteristics (ROC) curve revealed area of 0.64 (95% CI 0.53-0.75) and 0.80 (95% CI 0.72-0.88) for measurements at 18-21 and 22-25 weeks, respectively (P<or=0.001). Sensitivities of 33.3% and 23% and negative predicting value (NPV) of 97.3% and 86.8% for delivery at <28 and <34 weeks gestation were reached for measurements at 18-21 weeks. Sensitivities of 71.4% and 38.2% and NPV of 99.1% and 91.4% for delivery at <28 and <34 weeks' gestation were reached for measurements at 22-25 weeks. Cervical length shortening analysis showed an area under ROC curve of 0.81 (95% CI 0.73-0.89) and best cut-off was at >or=2 mm/week. Sensitivities of 80% and 60.8% and NPV of 98.9% and 90.6% for delivery at <28 and <34 weeks gestation were reached. In twin gestations, assessment of CL at 22-25 weeks is better than assessment at 18-21 weeks to predict preterm delivery before 34 weeks. Cervical shortening at a rate of >or=2 mm/weeks between 18 and 25 weeks gestat...Continue Reading

References

Aug 1, 1990·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J S YounisG Zajicek
Oct 1, 1990·British Journal of Obstetrics and Gynaecology·C A CrowtherH M Ashurst
Nov 25, 1997·American Journal of Obstetrics and Gynecology·V BerghellaR J Wapner
Jun 1, 2000·Obstetrics and Gynecology·A Conde-AgudeloG Lindmark
Nov 21, 2000·American Journal of Obstetrics and Gynecology·E R GuzmanA M Vintzileos
Mar 14, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C SkentouK H Nicolaides
Apr 23, 2002·American Journal of Obstetrics and Gynecology·Roger B NewmanDaniel L McGee
Sep 13, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Mariza M FujitaMarcelo Zugaib
Feb 26, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M H B CarvalhoM Zugaib
Oct 31, 2003·American Journal of Obstetrics and Gynecology·Barbara LukeShirley Gogliotti
Mar 17, 2004·Clinical Obstetrics and Gynecology·Barbara Luke, Joyce A Martin
Jun 2, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J L GibsonF Mackenzie
May 26, 2005·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ashley S RomanVincenzo Berghella
Aug 2, 2005·Obstetrical & Gynecological Survey·Allen Ayres, Timothy R B Johnson
May 2, 2006·American Journal of Obstetrics and Gynecology·Meekai S ToKypros H Nicolaides
Aug 3, 2007·The New England Journal of Medicine·Dwight J RouseUNKNOWN National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network

❮ Previous
Next ❯

Citations

Jun 14, 2015·American Journal of Obstetrics and Gynecology·Agustin Conde-Agudelo, Roberto Romero
Jul 30, 2014·American Journal of Obstetrics and Gynecology·Agustin Conde-Agudelo, Roberto Romero
Apr 30, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohamed Nabih El-Gharib, Sherin Barakat Albehoty
Oct 27, 2016·American Journal of Obstetrics and Gynecology·Leslie A MorozCynthia Gyamfi-Bannerman
Oct 31, 2013·Journal of Perinatal Medicine·Joana Barros-SilvaAlexandra Matias
Nov 26, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·César MellerLucas Otaño
Sep 28, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·César MellerLucas Otaño

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Disease in Childhood. Fetal and Neonatal Edition
Rosemarie A BolandVictorian Infant Collaborative Study Group
International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
J N Lee, T Chard
Journal of the American Academy of Nurse Practitioners
Patricia O CorbettJeanne Kemppainen
© 2021 Meta ULC. All rights reserved