Two-step wiring plasticity--a mechanism for estrogen-induced rewiring of cortical circuits

The Journal of Steroid Biochemistry and Molecular Biology
Deepak P Srivastava

Abstract

Estrogens have been shown to exert powerful effects on cognitive behaviors mediated by several areas of the brain including the cortex. Remodeling of spiny synapses is a key step in the rewiring of neuronal circuitry thought to underlie the processing and storage of information in the forebrain. Whereas estrogen has been shown to regulate synapse structure and function, we are only just starting to understand the molecular and cellular underpinnings of how estrogens can modulate neuronal circuits. Here I will review recent molecular and cellular work that offers a potential mechanism of how estrogen may modulate synapse structure and function of cortical neurons. This mechanism allows cortical neurons to respond to activity-dependent stimuli with greater efficacy in a cellular model termed "Two-Step Wiring Plasticity". This novel form of spine plasticity thus provides insight into how estrogens may modulate the rewiring of neuronal circuits, underlying its ability to influencing cortically based behaviors. This article is part of a Special Issue entitled 'Neurosteroids'.

References

Dec 16, 2000·The Journal of Comparative Neurology·T A MilnerS E Alves
Jun 18, 2003·Endocrinology·Victoria N LuineNeil J Maclusky
Jul 2, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Oliver KretzGabriele M Rune
Jul 6, 2004·Molecular and Cellular Neurosciences·Ayumu Tashiro, Rafael Yuste
Oct 16, 2004·Nature·D B ChklovskiiK Svoboda
Jan 25, 2005·Neuron·Anthony J G D HoltmaatKarel Svoboda
Dec 14, 2005·Neuroscience·G M Rune, M Frotscher
Dec 20, 2005·Current Opinion in Neurobiology·Tomoko Tada, Morgan Sheng
Jan 24, 2006·Neuroscience·J G YagueI Azcoitia
Apr 4, 2006·Trends in Neurosciences·Jacques Balthazart, Gregory F Ball
Aug 22, 2006·Annual Review of Pharmacology and Toxicology·Catherine S Woolley
Aug 23, 2006·Proceedings of the National Academy of Sciences of the United States of America·Jean-Vincent Le Bé, Henry Markram
May 26, 2007·Proceedings of the National Academy of Sciences of the United States of America·Brian C TrainorRandy J Nelson
Nov 6, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Klaus A MiczekAdrian Raine
Apr 12, 2008·Brain Research·Josue G YagueJohn H Morrison
Jul 4, 2008·Trends in Neurosciences·Peter Penzes, Kelly A Jones
Aug 15, 2008·Trends in Cell Biology·Peter PenzesDeepak P Srivastava
Sep 20, 2008·Proceedings of the National Academy of Sciences of the United States of America·Deepak P SrivastavaPeter Penzes
Sep 27, 2008·Trends in Neurosciences·William M DeBello
Sep 30, 2008·Nature Neuroscience·Luke Remage-HealeyBarney A Schlinger
Mar 21, 2009·Trends in Pharmacological Sciences·Roberta Diaz Brinton
Jun 16, 2009·Current Opinion in Neurobiology·Yoshihiro YoshiharaDominique Muller
Aug 21, 2009·Nature Reviews. Neuroscience·Anthony Holtmaat, Karel Svoboda
Nov 6, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kelly A JonesPeter Penzes
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Luke Remage-HealeyBarney A Schlinger
Aug 27, 2010·Annals of the New York Academy of Sciences·Dani DumitriuJohn H Morrison
Nov 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Daphne BavelierTakao K Hensch
Dec 1, 2010·Molecular and Cellular Neurosciences·Peter PenzesDeepak P Srivastava

❮ Previous
Next ❯

Citations

Sep 11, 2014·Hormones and Behavior·Victoria N Luine
Apr 1, 2014·Fertility and Sterility·Barbara FischerSanjay Asthana
Sep 18, 2012·Frontiers in Neuroendocrinology·Victoria N Luine, Maya Frankfurt
Jul 1, 2015·Hormones and Behavior·Kelsy S J ErvinElena Choleris
Jul 15, 2015·Hormones and Behavior·Jeffrey A BlairGemma Casadesus
Jul 5, 2013·Journal of Neuroendocrinology·D P Srivastava, P D Evans
Aug 28, 2014·Frontiers in Neuroendocrinology·Katherine SellersDeepak P Srivastava
Feb 22, 2017·Reviews in Endocrine & Metabolic Disorders·John Jacob Cannell
Oct 1, 2013·Pharmacological Reviews·Deepak P SrivastavaPeter Penzes
May 11, 2017·Journal of Neuroendocrinology·P A S SheppardE Choleris
Jul 6, 2017·Frontiers in Synaptic Neuroscience·Ahmet S Ozcan
Mar 20, 2019·Molecular Brain·Paul A S SheppardLiisa A M Galea

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Deepak P SrivastavaPeter Penzes
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Deepak P SrivastavaPeter Penzes
© 2022 Meta ULC. All rights reserved