Two weeks of repetitive gut-challenge reduce exercise-associated gastrointestinal symptoms and malabsorption

Scandinavian Journal of Medicine & Science in Sports
Atlanta MiallRicardo J S Costa

Abstract

Debilitating gastrointestinal symptoms is a common feature of endurance running and may be exacerbated by and/or limit the ability to tolerate carbohydrate intake during exercise. The study aimed to determine whether two weeks of repetitive gut-challenge during running can reduce exercise-associated gastrointestinal symptoms and carbohydrate malabsorption. Endurance runners (n=18) performed an initial gut-challenge trial (GC1) comprising 2-hour running exercise at 60% VO2max (steady state) while consuming a formulated gel-disk containing 30 g carbohydrates (2:1 glucose-fructose, 10% w/v) every 20 minutes, followed by a 1-hour running effort bout. Gastrointestinal symptoms, feeding tolerance, and breath hydrogen (H2 ) were determined along the gut-challenge trial. After GC1, participants were randomly assigned to a blinded carbohydrate (CHO, 90 gCHO hour-1 ) or placebo (PLA, 0 gCHO hour-1 ) gut-training group. This comprised of consuming the group-specific feeding intervention during 1-hour running exercise at 60% VO2max equivalent, daily over a period of two weeks. Participants then repeated the gut-challenge trial (GC2). In GC2, a reduced gut discomfort (P=.012), total (P=.009), upper- (P=.015), and lower-gastrointestinal (P=....Continue Reading

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Citations

Sep 27, 2018·International Journal of Sport Nutrition and Exercise Metabolism·Louise M BurkeRonald J Maughan
Oct 16, 2018·Research in Sports Medicine·C BlennerhassettS A Sparks
Jan 12, 2019·International Journal of Sport Nutrition and Exercise Metabolism·Stephanie K GaskellRicardo J S Costa
Oct 10, 2018·Medicine and Science in Sports and Exercise·Kristin L JonvikLex B Verdijk
Jan 1, 2020·International Journal of Sport Nutrition and Exercise Metabolism·Alan J McCubbinLouise M Burke
Oct 28, 2019·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Stephanie K GaskellRicardo J S Costa
Apr 15, 2019·European Journal of Applied Physiology·Jamie N PughGraeme L Close
Jul 31, 2018·Research in Sports Medicine·Ricardo J S CostaTrent Stellingwerff
Jun 12, 2020·Journal of the International Society of Sports Nutrition·Jill A ParnellKelly Anne Erdman
Sep 30, 2018·European Journal of Applied Physiology·Martin D HoffmanRicardo J S Costa
Jan 28, 2021·Sports Medicine·Nicholas B TillerGuillaume Y Millet
Oct 17, 2020·Medicine and Science in Sports and Exercise·Stephanie K GaskellRicardo J S Costa
May 29, 2021·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Rachel ScrivinGary Slater
Jun 3, 2021·International Journal of Environmental Research and Public Health·Soledad ArribalzagaJuan Mielgo-Ayuso

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