Two-year clinical outcomes following lower limb endovascular revascularisation for chronic limb threatening ischaemia at a tertiary Asian vascular centre in Singapore

Singapore Medical Journal
Wei Ling TayTjun Y Tang

Abstract

Percutaneous transluminal angioplasty (PTA) is commonly used to treat patients with chronic limb-threatening ischaemia (CLTI). This study aimed to examine mortality and functional outcomes in a multi-ethnic Asian population from Singapore of CLTI patients who predominantly had diabetes mellitus. CLTI patients who underwent PTA between January 2015 and March 2017 at the Vascular Unit at Singapore General Hospital, Singapore, were studied. Primary outcome measures were 30-day unplanned readmission, two-year major lower extremity amputation (LEA), mortality rates, and ambulation status at one, six and 12 months. 221 procedures were performed on 207 patients, of whom 184 (88.9%) were diabetics. One-, six- and 12-month mortality was 7.7%, 16.4% and 21.7%, respectively. The two-year LEA rate was 30.0%. At six and 12 months, only 96 (46.4%) and 93 (44.9%) patients were ambulant, respectively. Multivariate analysis revealed that preoperative ambulatory status; haemoglobin; Wound Ischaemia and foot Infection (WIfI) score; and end-stage renal failure (ESRF) were independent predictors for one-year ambulatory status. Predictors of mortality at one, six and 12 months were ESRF, preoperative albumin level, impaired functional status and emp...Continue Reading

Citations

Apr 13, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Tjun Yip TangTze Tec Chong
Jun 1, 2021·International Angiology : a Journal of the International Union of Angiology·Tjun Y TangChuo R Leong

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