Two-year data comparison of ab interno trabeculectomy and trabecular bypass stenting using exact matching

Journal of Cataract and Refractive Surgery
Hamed EsfandiariNils A Loewen

Abstract

To create a balanced comparison of ab interno trabeculectomy (AIT) (Trabectome) and trabecular bypass stenting (TBS) (iStent). Eye and Ear Institute, Pittsburgh, Pennsylvania, Ross Eye Institute, Buffalo, New York, and Glaucoma Associates of Texas, Dallas, USA. Retrospective case series. The primary outcome measure was an unmedicated intraocular pressure (IOP) of 21 mm Hg or less and the secondary measure was an unmedicated IOP reduction of 20% or more at 2 years. Patients were matched by baseline IOP, number of glaucoma medications, and glaucoma type using exact matching and by age using nearest neighbor matching. Individuals without a close match were excluded. All surgeries were combined with phacoemulsification. One hundred fifty-four AIT eyes and 110 TBS eyes were analyzed. Forty-eight AIT patients were exactly matched with 48 TBS patients. Both groups had a mean baseline IOP of 15.3 mm Hg ± 3.1 (SD). At 24 months, the mean IOP was 13.9 ± 3.3 mm Hg in AIT patients and 16.8 ± 2.8 mm Hg in TBS patients and the mean number of medications was 0.7 ± 1.0 and 1.7 ± 1.2, respectively (both P = .04). At 24 months, the IOP was 21 mm Hg or less without medications in 53% of AIT patients and 16.6% of TBS patients (P < .05). At that ti...Continue Reading

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Citations

Dec 27, 2019·Journal of Glaucoma·Arvi-Matti KuusniemiMika Harju
Sep 23, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yousef Al YousefNils A Loewen
Aug 22, 2020·Translational Vision Science & Technology·Chen XinNing-Li Wang
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Nov 6, 2020·Japanese Journal of Ophthalmology·Masayuki Kasahara, Nobuyuki Shoji

Related Concepts

Buffaloes
Pharmaceutical Preparations
Eye
Glaucoma
Physiologic Intraocular Pressure
Mercury
Trabeculectomy
Proximal
Trabecular Substance of Bone
Phacoemulsification

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