Two-year follow-up of changes in clinical chemistry in Singaporean Norplant acceptors: haemostatic changes

Contraception
K SinghS S Ratnam

Abstract

A longitudinal study of coagulation parameters was carried out on 100 Singaporean acceptors using Norplant for contraceptive purposes. At the end of 2 years of use, results from this ongoing study indicate that these acceptors continue to have an increased predisposition to thrombosis as evidenced by significant increases in platelet count and aggregability. The shortened but stable prothrombin time and activated partial thromboplastin time and increase in certain coagulation factors indicate that Norplant acceptors still have a possible potential for hypercoagulation at the end of two years of use.

References

Sep 1, 1970·British Journal of Haematology·R BiggsM Hadden
Aug 1, 1971·British Journal of Haematology·K W DensonR Biggs
Jan 1, 1955·British Journal of Haematology·R BIGGSG RICHARDS
Feb 1, 1961·Acta Haematologica·K W DENSON
Aug 1, 1963·The Journal of Physiology·G V BORN, M J CROSS

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Citations

Mar 1, 1990·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·K SinghS S Ratnam
Feb 28, 2002·Contraception·Laneta J Dorflinger
Aug 11, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A O AisienM O Shobowale
Sep 23, 2008·Expert Review of Medical Devices·Giuseppe BenagianoManuela Farris

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