Two-year follow-up of changes in clinical chemistry in Singaporean Norplant-2 rod acceptors: haemostatic changes

Contraception
K SinghS S Ratnam

Abstract

A longitudinal study of coagulation parameters was carried out on 100 Singaporean acceptors using Norplant-2 rods for contraceptive purposes. At the end of 2 years of use, results from this study show a return of platelet count to preinsertion level while platelet aggregation remained significantly enhanced. Thus the net effect of these two changes on an increased tendency for thrombosis needs further evaluation. The PT and APTT continued to remain persistently shortened during the period of use. There was also a general fall in fibrinogen and most other coagulation factors during the two years of use. Thus, again, the net effect of these two changes on the exposed potential for hypercoagulation at the end of the first year needs further evaluation throughout the five years of Norplant-2 use.

References

Sep 1, 1970·British Journal of Haematology·R BiggsM Hadden
Aug 1, 1971·British Journal of Haematology·K W DensonR Biggs
Jan 1, 1955·British Journal of Haematology·R BIGGSG RICHARDS
Feb 1, 1961·Acta Haematologica·K W DENSON
Aug 1, 1963·The Journal of Physiology·G V BORN, M J CROSS

❮ Previous
Next ❯

Citations

Jun 1, 1990·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·K SinghS S Ratnam
Feb 28, 2002·Contraception·Laneta J Dorflinger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Coagulation Signaling Pathways

Coagulation is the process by which a blood clot is formed. This process includes both the formation of a platelet plug as well as a cascade of clotting factors resulting in the formation of fibrin strands. Find the latest research on coagulation signaling pathways here.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception
K SinghS S Ratnam
Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception
K SinghS S Ratnam
© 2022 Meta ULC. All rights reserved