Two-Year Outcomes of XEN Gel Stent Surgery in Patients with Open-Angle Glaucoma.

Ophthalmology. Glaucoma
Kaweh MansouriAndré Mermoud

Abstract

To evaluate the 2-year treatment outcomes of the XEN gel stent (Allergan, Inc, Irvine, CA) in glaucoma patients. Prospective, single-center interventional study. One hundred forty-nine eyes of 113 patients with open-angle glaucoma. Consecutive eyes with uncontrolled intraocular pressure (IOP) or signs of disease progression despite medical treatment were included to undergo either standalone XEN implantation or combined XEN implantation plus phacoemulsification surgery, both with mitomycin C injections. Primary efficacy outcome was success, defined as complete when the unmedicated IOP was 12 mmHg or less, 15 mmHg or less, or 18 mmHg or less and 20% lower than at baseline over the 2-year period and defined as qualified when the IOP fulfilled the same conditions with fewer medications than at baseline. Secondary measures were mean reduction in IOP and in the number of medications and the rates of reoperations. One hundred nine eyes (84 patients; mean age, 74.3 years) underwent XEN plus phacoemulsification surgery and 40 eyes (29 patients; mean age, 74.7 years) underwent standalone XEN surgery. Overall, 129 eyes (86.6%; 96 eyes of 75 XEN plus phacoemulsification patients and 33 eyes of 24 XEN standalone surgery patients) completed...Continue Reading

Citations

May 8, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Giorgio Enrico BravettiAndré Mermoud
Nov 9, 2019·Journal of Glaucoma·Neha MidhaKaweh Mansouri
Apr 4, 2021·Journal of Clinical Medicine·Huub J PoelmanWishal D Ramdas
Sep 16, 2020·Acta Ophthalmologica·Kevin GillmannKaweh Mansouri
Aug 20, 2021·PloS One·Boonsong Wanichwecharungruang, Nitee Ratprasatporn
Sep 28, 2021·Klinische Monatsblätter für Augenheilkunde·Caroline BormannJan Darius Unterlauft

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