Two-Year Results of Think Health! ¡Vive Saludable!: A Primary Care Weight-Management Trial

Obesity
Shiriki KumanyikaThomas A Wadden

Abstract

Think Health! ¡Vive Saludable! evaluated a moderate-intensity, lifestyle behavior-change weight-loss program in primary care over 2 years of treatment. Final analyses examined weight-change trajectories by treatment group and attendance. Adult primary care patients (n = 261; 84% female; 65% black; 16% Hispanic) were randomly assigned to Basic Plus (moderate intensity; counseling by primary care clinician and a lifestyle coach) or Basic (clinician counseling only). Intention-to-treat analyses used all available weight measurements from data collection, treatment, and routine clinical visits. Linear mixed-effects regression models adjusted for treatment site, gender, and age, and sensitivity analyses evaluated treatment attendance and the impact of loss to follow-up. Model-based estimates for 24-month mean (95% CI) weight change from baseline were -1.34 kg (-2.92 to 0.24) in Basic Plus and -1.16 kg (-2.70 to 0.37) in Basic (net difference -0.18 kg [-2.38 to 2.03]; P = 0.874). Larger initial weight loss in Basic Plus was attenuated by a ~0.5-kg rebound at 12 to 16 months. Each additional coaching visit was associated with a 0.37-kg greater estimated 24-month weight loss (P = 0.01). These findings in mostly black and Hispanic femal...Continue Reading

Associated Clinical Trials

References

Sep 1, 1978·American Journal of Epidemiology·R S PaffenbargerR T Hyde
Aug 1, 1967·Journal of Psychosomatic Research·T H Holmes, R H Rahe
Dec 1, 1983·Journal of Health and Social Behavior·S CohenR Mermelstein
Feb 12, 2002·Obesity Research·Shiriki K KumanyikaUNKNOWN TONE Cooperative Research Group
May 27, 2005·Preventive Medicine·Shiriki K KumanyikaMarjorie A Bowman
May 1, 2007·Journal of the American Dietetic Association·Cheryl A M AndersonPatricia M Risica
Jun 30, 2009·Journal of General Internal Medicine·Adam Gilden Tsai, Thomas A Wadden
Oct 28, 2009·Archives of Internal Medicine·Shiriki K KumanyikaXiaoying Wu
May 3, 2011·The Annals of Applied Statistics·Michael ParzenJoseph G Ibrahim
Nov 16, 2011·The New England Journal of Medicine·Thomas A WaddenReneé H Moore
Nov 17, 2011·The New England Journal of Medicine·Lawrence J AppelFrederick L Brancati
Mar 14, 2012·Archives of Internal Medicine·Gary G BennettUNKNOWN Be Fit, Be Well Study Investigators
Sep 10, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·C D Samuel-HodgeM Lackey
Nov 5, 2014·JAMA : the Journal of the American Medical Association·Thomas A WaddenAdam G Tsai
Jun 26, 2015·Obesity·Jessica L UnickUNKNOWN Look AHEAD Research Group
Feb 21, 2016·Journal of Racial and Ethnic Health Disparities·John M McLaughlinBartholomew Tortella
Jan 19, 2017·The New England Journal of Medicine·Steven B Heymsfield, Thomas A Wadden

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Citations

Mar 20, 2019·Current Obesity Reports·Jena Shaw TronieriAdam Gilden Tsai
Aug 4, 2019·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Shiriki Kumanyika
Nov 26, 2019·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Hope E M SchwartzSeth A Gale
Oct 3, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Raquel CanutoMaria Teresa Anselmo Olinto
Jul 24, 2021·Current Obesity Reports·Shanna TuckerMelanie Jay

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Software Mentioned

POWER
Basic
Stata
SAS
Basic Plus
UP

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