Two (Z)-dehydrobutyrine-containing microcystins from a hepatotoxic bloom of Oscillatoria agardhii from Soulseat Loch, Scotland

Journal of Natural Products
T SanoK Kaya

Abstract

Two (Z)-dehydrobutyrine(Dhb)-containing microcystins, [d-Asp3, (Z)-Dhb7]microcystin-HtyR (1) and [d-Asp3, (Z)-Dhb7]microcystin-LR (2), were isolated from a hepatotoxic bloom of the cyanobacterium Oscillatoria agardhii from a freshwater lake in Scotland. The geometrical structure of the Dhb units in the microcystins was determined as Z on the basis of NOE and ROESY experiments.

Citations

Jan 4, 2001·Toxicon : Official Journal of the International Society on Toxinology·P MehtoJ Meriluoto
Feb 9, 2000·Toxicon : Official Journal of the International Society on Toxinology·R J MorriS E Calvert
Feb 1, 2003·Aquatic Toxicology·Kenneth A BeattieStephan Pflugmacher
Apr 17, 2007·Journal of Natural Products·Tianying AnKathleen S Rein
Mar 15, 2005·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Ronald W ZurawellEllie E Prepas
May 2, 2014·Journal of the American Society for Mass Spectrometry·Yulin QiDietrich A Volmer
Apr 20, 2014·Proceedings of the National Academy of Sciences of the United States of America·Johanna VestolaKaarina Sivonen
Sep 1, 2004·Journal of Separation Science·Takuya KuboKunimitsu Kaya
Jul 29, 2004·Phytochemistry·Tomoharu SanoKunimitsu Kaya
Nov 18, 2003·Annual Review of Genetics·J L DittyS S Golden
Oct 18, 2014·Amino Acids·Dawid Siodłak
Jun 3, 2014·European Journal of Mass Spectrometry·Stella Bortoli, Dietrich A Volmer
May 31, 2006·Journal of Peptide Science : an Official Publication of the European Peptide Society·Malgorzata A BrodaBarbara Rzeszotarska
Dec 14, 2007·Angewandte Chemie·Karolina ErsmarkStephen Hanessian
Jan 29, 2009·Biopolymers·Fateh S Nandel, Tammanna R Sahrawat
Jan 7, 2005·Journal of Peptide Science : an Official Publication of the European Peptide Society·Małgorzata A BrodaBarbara Rzeszotarska
Oct 29, 2004·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Takuya KuboKunimitsu Kaya
Dec 22, 2009·Chemical Communications : Chem Comm·Shuo LiangTao Ye
May 2, 2001·Journal of Chromatography. a·L A Lawton, C Edwards
Apr 18, 2020·Environmental Science & Technology·Regiane Natumi, Elisabeth M-L Janssen

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